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[伴刀豆球蛋白A对欧洲肋突螈(两栖纲,有尾目)囊胚发育的影响]

[Effect of concanavalin A on the development of blastulae in Pleurodeles waltlii (Amphibia, Urodeles)].

作者信息

Boucaut J C, Bernard B, Aubery M

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Jul 11;285(2):193-6.

PMID:409552
Abstract

The effect of concanavalin A (con A) on Pleurodeles waltlii blastulae was studied by incubating the eggs in presence of lectin. It was found that the protein exercised an inhibitory effect upon morphogenesis. This inhibition was concentration dependent. In certain cases, the inhibitory effect of con A was attenuated by alpha-D-methyl-mannose (0,05 M).

摘要

通过在伴刀豆球蛋白A(伴刀豆凝集素A,con A)存在的情况下孵育卵,研究了其对非洲爪蟾囊胚的影响。发现该蛋白质对形态发生具有抑制作用。这种抑制作用是浓度依赖性的。在某些情况下,α-D-甲基甘露糖(0.05M)可减弱con A的抑制作用。

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