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不对称茎突导致双侧颈动脉夹层:一例罕见病例报告,强调长度以外解剖因素的作用

Bilateral Carotid Artery Dissection Due to Asymmetric Styloid Processes: A Rare Case Report Highlighting the Role of Anatomical Factors Beyond Length.

作者信息

Kitamura Kazushi, Iwasaki Koichi, Mikami Kazuyuki, Hasegawa Hiroshi, Sasaki Isao

机构信息

Neurosurgery, Ainomiyako Neurosurgery Hospital, Osaka, JPN.

出版信息

Cureus. 2025 Aug 15;17(8):e90185. doi: 10.7759/cureus.90185. eCollection 2025 Aug.

DOI:10.7759/cureus.90185
PMID:40955242
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12433720/
Abstract

Elongation of the styloid process (SP) is a recognized etiologic factor in vascular pathologies such as carotid artery dissection (CAD), particularly in Eagle syndrome or stylocarotid artery syndrome. However, CAD involving an SP of normal length is exceedingly rare and often overlooked in clinical evaluations. We present a unique case of bilateral CAD caused by mechanical injury from asymmetric SPs - one elongated and the other of normal length - challenging the conventional belief that only elongated SPs carry clinical importance. A 47-year-old female patient experienced sequential episodes of bilateral CAD over a seven-month period. Radiological evaluations identified bilateral CAD likely attributed to the left SP of normal length (22 mm) and the right SP with elongation (35 mm). Both SPs were located in close proximity (<1 mm) to their respective internal carotid arteries (ICAs). Notably, despite its normal length, the left SP had a steep medial angulation of 65.1°, contributing to the ICA impingement. To restore vascular patency and prevent recurrence, the patient underwent successful bilateral carotid artery stenting followed by transcervical styloidectomies. While elongated SPs are commonly implicated in unilateral vascular symptoms, bilateral CAD related to SP impingement is rare. This case illustrates that even an SP of normal length can cause vascular injury when it exhibits atypical angulation and lies in close proximity to the ICA. Contrary to the conventional belief that only SP elongation has clinical importance, SPs of normal length may play a pathogenic role in SP-related CAD under specific anatomical conditions. We emphasize the importance of a comprehensive radiological evaluation that focuses not solely on SP length when considering potential SP-related vascular pathology.

摘要

茎突延长是诸如颈动脉夹层(CAD)等血管病变公认的病因,尤其是在鹰综合征或茎突颈动脉综合征中。然而,涉及正常长度茎突的CAD极为罕见,在临床评估中常被忽视。我们报告了一例独特的双侧CAD病例,病因是不对称茎突造成的机械损伤——一个茎突延长,另一个长度正常——这挑战了传统观念,即只有延长的茎突才具有临床意义。一名47岁女性患者在七个月内先后出现双侧CAD发作。影像学评估确定双侧CAD可能归因于长度正常(22毫米)的左侧茎突和延长(35毫米)的右侧茎突。两个茎突均与其各自的颈内动脉(ICA)紧邻(<1毫米)。值得注意的是,尽管左侧茎突长度正常,但其向内侧有65.1°的陡峭角度,导致ICA受压。为恢复血管通畅并防止复发,患者成功接受了双侧颈动脉支架置入术,随后进行了经颈茎突切除术。虽然延长的茎突通常与单侧血管症状有关,但与茎突压迫相关的双侧CAD很少见。该病例表明,即使是正常长度的茎突,当其呈现非典型角度且紧邻ICA时,也可导致血管损伤。与只有茎突延长具有临床重要性的传统观念相反,在特定解剖条件下,正常长度的茎突可能在与茎突相关的CAD中起致病作用。我们强调,在考虑潜在的与茎突相关的血管病变时,全面的影像学评估非常重要,不能仅关注茎突长度。

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本文引用的文献

1
Styloid process-related internal carotid artery dissection: extensive literature review of diagnosis, treatment and outcomes (exemplified with a single-center case series).茎突相关的颈内动脉夹层:关于诊断、治疗及预后的广泛文献综述(以单中心病例系列为例)
Neuroradiology. 2025 Apr 26. doi: 10.1007/s00234-025-03616-y.
2
Internal carotid artery dissection leading to occlusion in a patient with nonelongated styloid process: illustrative case.茎突未延长患者因颈内动脉夹层导致闭塞:病例说明
J Neurosurg Case Lessons. 2025 Jan 13;9(2). doi: 10.3171/CASE24719.
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Vascular variant of Eagle syndrome: a review.
鹰综合征的血管变异型:综述
Front Neurol. 2024 Oct 8;15:1463275. doi: 10.3389/fneur.2024.1463275. eCollection 2024.
4
Surgical management of stylocarotid Eagle syndrome in a patient with bilateral internal carotid artery dissection: illustrative case.双侧颈内动脉夹层患者茎突颈动脉型鹰综合征的外科治疗:病例说明
J Neurosurg Case Lessons. 2024 Jan 29;7(5). doi: 10.3171/CASE23682.
5
Eagle syndrome: An updated review.鹰嘴综合征:最新综述。
Surg Neurol Int. 2023 Nov 3;14:389. doi: 10.25259/SNI_666_2023. eCollection 2023.
6
Stylalgia and Styloidectomy: A Review.茎突痛与茎突切除术:综述
J Maxillofac Oral Surg. 2023 Mar;22(1):60-66. doi: 10.1007/s12663-022-01720-7. Epub 2022 Apr 26.
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Fracture of a Flow Diverter in the Cervical Internal Carotid Artery Due to Eagle Syndrome.因鹰综合征导致的颈内动脉血流分流器骨折
Neurointervention. 2023 Mar;18(1):72-75. doi: 10.5469/neuroint.2022.00409. Epub 2023 Jan 10.
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Bilateral carotid dissection due to Eagle syndrome in a young female.一名年轻女性因鹰综合征导致双侧颈动脉夹层。
eNeurologicalSci. 2021 Jun 16;24:100353. doi: 10.1016/j.ensci.2021.100353. eCollection 2021 Sep.
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Internal carotid artery dissection related to abnormalities of styloid process: is it only a matter of length?与茎突异常相关的颈内动脉夹层:仅仅是长度问题吗?
Neurol Sci. 2022 Jan;43(1):459-465. doi: 10.1007/s10072-021-05350-8. Epub 2021 May 31.
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Dynamic assessment of internal carotid artery and elongated styloid process in a case of bilateral carotid artery dissection.双侧颈动脉夹层一例中颈内动脉及茎突过长的动态评估
Surg Neurol Int. 2020 Jun 27;11:163. doi: 10.25259/SNI_42_2020. eCollection 2020.