Fatmi Warda, Kumari Usha, Shahid Shehroz, Waseem Maria, Mukhtar Qamar Un Nisa
Civil Hospital Karachi, Pakistan.
Dow University of Health Sciences, Karachi, Pakistan.
Clin Med Insights Case Rep. 2025 Sep 12;18:11795476251359429. doi: 10.1177/11795476251359429. eCollection 2025.
Dengue virus infection is a significant public health concern, particularly in endemic areas. This case report highlights the difficulties in diagnosing expanded dengue syndrome (EDS) in a dengue-endemic region. This case report emphasizes keeping high suspicion of index for (EDS) among patients presenting with fever and neurological manifestations particularly in regions where dengue is endemic. The atypical neurological symptoms and inconclusive initial investigations underscore the diagnostic challenges associated with (EDS). Prompt recognition and appropriate laboratory testing, such as detecting dengue NS1 antigen, can aid in accurate diagnosis and subsequent management of patients with this condition. Increased awareness among healthcare providers in endemic regions is crucial for timely identification and intervention in case of dengue-associated neurological complications. Therefore, a multidisciplinary approach is required for time-effective management.
登革病毒感染是一个重大的公共卫生问题,在流行地区尤为如此。本病例报告强调了在登革热流行地区诊断扩展型登革热综合征(EDS)的困难。本病例报告强调,对于出现发热和神经症状的患者,尤其是在登革热流行地区,要高度怀疑其患有(EDS)。非典型神经症状和初步检查结果不明确凸显了与(EDS)相关的诊断挑战。及时识别并进行适当的实验室检测,如检测登革热NS1抗原,有助于准确诊断并对患有这种疾病的患者进行后续管理。提高流行地区医护人员的意识对于及时识别登革热相关神经并发症并进行干预至关重要。因此,需要采用多学科方法进行高效管理。