Pungpak S, Riganti M, Bunnag D, Harinasuta T
Southeast Asian J Trop Med Public Health. 1985 Sep;16(3):405-9.
Clinical features of severe opisthorchiasis were studied in 88 patients. The ratio of males to females was 6.3 : 1; 75% were over 40 years old. The presenting symptoms were obstructive jaundice, 25% associated with secondary infection of biliary system; cholangitis and cholecystitis; intraabdominal mass, which was enlarged liver; 18% had palpable gallbladder; 18% had adenocarcinoma of the bile duct. High bilirubin was found in 46% of cases, high alkaline phosphatase in 80%; elevation of serum transaminase in 78% and low serum albumin in 62% of patients. There was no correlation between severity of the disease and the faecal egg output. The obstructive jaundice patients had low or no egg output. Two patients had no eggs in stool, but numerous Opisthorchis viverrini eggs and flukes were found in the gallbladder and bile ducts at operation.
对88例严重华支睾吸虫病患者的临床特征进行了研究。男女比例为6.3:1；75%的患者年龄超过40岁。主要症状为梗阻性黄疸，25%伴有胆道系统继发感染；胆管炎和胆囊炎；腹腔肿块，即肝脏肿大；18%可触及胆囊；18%患有胆管腺癌。46%的病例胆红素升高，80%碱性磷酸酶升高；78%的患者血清转氨酶升高，62%的患者血清白蛋白降低。疾病严重程度与粪便虫卵排出量之间无相关性。梗阻性黄疸患者的虫卵排出量低或无虫卵排出。两名患者粪便中无虫卵，但手术时在胆囊和胆管中发现大量猫后睾吸虫虫卵和虫体。
