Hosny Rawan, Saad Maha
Department of Ophthalmology, Kasr AlAiny Hospital, Cairo University, Cairo, 11956, Egypt.
BMC Ophthalmol. 2025 Sep 16;25(1):504. doi: 10.1186/s12886-025-04337-9.
Steroids are arguably one of the most important drugs in modern medicine, utilized in many disorders. Their use, however, is not without complications. Medically unsupervised misuse of corticosteroids can have devastating, potentially fatal complications. We report a case of a 27-year-old female with history of bariatric surgery and extensive weight loss 10 years prior to her presentation at Kasr Al Ainy, Cairo University Hospitals, Emergency Department (ED). She decided, without seeking medical advice, to take 90 mg oral prednisolone to gain weight 3 months before presenting with left corneal melting and perforation. Emergency tectonic graft surgery was done to salvage globe.
类固醇可以说是现代医学中最重要的药物之一，被用于多种疾病的治疗。然而，其使用并非没有并发症。在无医学监督的情况下滥用皮质类固醇可能会导致毁灭性的、甚至可能致命的并发症。我们报告一例27岁女性病例，该患者有减肥手术史，在开罗大学医院卡斯尔艾尼分院急诊科就诊前10年体重大幅减轻。在未寻求医疗建议的情况下，她决定在出现左眼角膜溶解和穿孔前3个月服用90毫克口服泼尼松龙以增加体重。为挽救眼球实施了急诊构造性移植手术。
