Finze Alida, Duddek Megan, Hetjens Svetlana, Ghanad Erfan, Reissfelder Christoph, Otto Mirko, Betzler Johanna, Joisten Christine, Blank Susanne
Department of Surgery, Medical Faculty Mannheim, Universitätsmedizin Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 60167, Mannheim, Germany.
Department of Medical Statistics, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
BMC Sports Sci Med Rehabil. 2025 Sep 16;17(1):265. doi: 10.1186/s13102-025-01307-y.
Cardiovascular disease and obesity-related comorbidities are key factors addressed by metabolic-bariatric surgery (MBS). Although High intensity interval training (HIIT) has been proven effective in healthy cohorts, limited evidence exists regarding HIIT and adherence towards HIIT after MBS. This study aims to test feasibility and cardiorespiratory effect of HIIT after MBS.
201 patients undergoing MBS were included in a four-week training protocol with 3 training groups (B-D) including different HIIT protocols on a bicycle designed for patients with obesity and one control group (A) at a university medical center in Germany. Ergometry with estimated VO2max, maximum blood lactate, maximum resistance, time spent on ergometer, and heart rate were performed prior to and after 4 weeks of training.
A significant effect of the four-week training could be shown through reduction of heart rate at 100 W, increase of maximum blood lactate, and maximum resistance when comparing the training groups to the control group (Δ 9,67 BPM; Δ 1.02 mmol/l; Δ 12 W respectively, all p < 0.05) However, adherence of the recruited patient group was very low, shown by a notably high drop-out rate of 78.1% overall (44 patients completed training). The majority of patients dropped out prior to the first training session.
HIIT bicycle training in post-MBS patients is possibly very effective, however, adherence is extremely low. Although this study shows promising results, an effect on large patient groups cannot be expected if improvement of adherence and a wide range of training methods are not addressed first.
German Registry for Clinical Trials (DRKS) trial registration number DRKS00024939 on 20/09/2021.
心血管疾病和肥胖相关合并症是代谢减重手术(MBS)解决的关键因素。尽管高强度间歇训练(HIIT)已在健康人群中被证明有效,但关于HIIT以及MBS后对HIIT的依从性的证据有限。本研究旨在测试MBS后HIIT的可行性和心肺效应。
201例接受MBS的患者被纳入一项为期四周的训练方案,该方案包括3个训练组(B - D),采用为肥胖患者设计的自行车上的不同HIIT方案,以及德国一家大学医学中心的1个对照组(A)。在训练4周前后进行运动测试,测量预计的最大摄氧量、最大血乳酸、最大阻力、在测力计上花费的时间和心率。
与对照组相比,训练组在100W时心率降低、最大血乳酸增加和最大阻力增加,显示出四周训练的显著效果(分别为Δ9.67次/分钟;Δ1.02mmol/L;Δ12W,均p < 0.05)。然而,招募的患者组的依从性非常低,总体退出率高达78.1%(44例患者完成训练)。大多数患者在第一次训练前就退出了。
MBS后患者进行HIIT自行车训练可能非常有效,然而,依从性极低。尽管本研究显示出有希望的结果,但如果不首先解决依从性的改善和广泛的训练方法问题,就不能期望对大量患者群体产生效果。
德国临床试验注册中心(DRKS)试验注册号DRKS00024939,于2021年9月20日注册。