Moez Abdul, Hussain Saddam, Ali Murad, Ahmed Sohail, Khan Adnan, Umer Muhammad Rizwan, Ishtiaq Hifza, Akbar Amna, Noor Palwasha, Khattak Muhammad Iftikhar, L Ayesha
Neurosurgery, Ghurki Hospital, Punjab, PAK.
Neurosurgery, Combined Military Hospital, Rawalakot, PAK.
Cureus. 2025 Aug 15;17(8):e90178. doi: 10.7759/cureus.90178. eCollection 2025 Aug.
Background Degenerative lumbar spine disease (DLSD) is a prevalent condition that significantly impacts quality of life. Surgical interventions, including microdiscectomy and open discectomy, are commonly used to treat symptomatic lumbar disc herniation. However, the comparative effectiveness of these procedures remains a subject of ongoing research. Objective This study aims to compare the clinical outcomes of microdiscectomy and open discectomy in patients with degenerative lumbar spine disease, focusing on pain relief, functional recovery, complications, and patient satisfaction. Methods A total of 600 patients (309 microdiscectomy, 291 open discectomy) were included in this prospective cohort study. Data were collected on demographic characteristics, preoperative and postoperative pain scores, functional recovery (measured by Oswestry Disability Index), and complications. Logistic regression and multiple linear regression models were employed to predict outcomes, and random forest analysis was used to identify key predictors of complications. Results Microdiscectomy was associated with significantly better postoperative outcomes, including reduced pain (213/309 (69%) vs. 146/291 (50%)), faster recovery (mean recovery time 5.2 weeks vs. 7.6 weeks), fewer complications (46/309 (14.9%) vs. 67/291 (23%)), and higher patient satisfaction (101/309 (32.8%) vs. 73/291 (25%)). Additionally, microdiscectomy also resulted in larger overall improvements in functional recovery and mobility scores compared to open discectomy. Conclusion Microdiscectomy provides superior results in pain relief, recovery time, and complication rates compared to open discectomy. This supports recommending microdiscectomy (with proper patient selection) for most patients with lumbar disc herniation.
背景 退行性腰椎疾病(DLSD)是一种普遍存在的疾病,对生活质量有重大影响。手术干预,包括显微椎间盘切除术和开放椎间盘切除术,常用于治疗有症状的腰椎间盘突出症。然而,这些手术的相对有效性仍是一个正在进行研究的课题。目的 本研究旨在比较显微椎间盘切除术和开放椎间盘切除术治疗退行性腰椎疾病患者的临床结果,重点关注疼痛缓解、功能恢复、并发症和患者满意度。方法 本前瞻性队列研究共纳入600例患者(309例行显微椎间盘切除术,291例行开放椎间盘切除术)。收集了人口统计学特征、术前和术后疼痛评分、功能恢复情况(采用Oswestry功能障碍指数测量)以及并发症的数据。采用逻辑回归和多元线性回归模型预测结果,并使用随机森林分析来识别并发症的关键预测因素。结果 显微椎间盘切除术与明显更好的术后结果相关,包括疼痛减轻(213/309(69%)对146/291(50%))、恢复更快(平均恢复时间5.2周对7.6周)、并发症更少(46/309(14.9%)对67/291(23%))以及患者满意度更高(101/309(32.8%)对73/291(25%))。此外,与开放椎间盘切除术相比,显微椎间盘切除术在功能恢复和活动度评分方面的总体改善也更大。结论 与开放椎间盘切除术相比,显微椎间盘切除术在疼痛缓解、恢复时间和并发症发生率方面提供了更好的结果。这支持对大多数腰椎间盘突出症患者推荐显微椎间盘切除术(在适当选择患者的情况下)。