深部脑刺激对帕金森病患者人格及执行功能的影响。
Effects of deep brain stimulation on personality and executive function in Parkinson's disease.
作者信息
Arten Thayná Laís de Souza, Hamdan Amer Cavalheiro
机构信息
Universidade Federal do Paraná, Setor de Ciências Humanas, Programa de Pós-Graduação em Psicologia, Curitiba PR, Brazil.
出版信息
Dement Neuropsychol. 2025 Sep 5;19:e20240254. doi: 10.1590/1980-5764-DN-2024-0254. eCollection 2025.
UNLABELLED
Parkinson's disease (PD) is associated with cognitive and personality changes that extend beyond its characteristic motor symptoms.
OBJECTIVE
To analyze the effects of subthalamic nucleus deep brain stimulation (STN-DBS) on executive function (EF) and personality (The Five-Factor Model - FFM) in PD patients, comparing outcomes between those treated solely with medication and those receiving both medication and STN-DBS.
METHODS
A total of 69 participants were divided into three groups: DBS, medication, and control. Evaluations included inventories, tests, and scales, with results summarized in tables highlighting sociodemographic variables and screening outcomes.
RESULTS
Cognitive assessments indicated that the DBS group exhibited slightly lower cognitive scores compared to the medication group. Personality differences were minimal, with only extraversion demonstrating significance.
CONCLUSION
STN-DBS did not have a significant impact on executive functions or personality traits in patients with PD. These results highlight the importance of considering broader cognitive and neuropsychiatric factors when evaluating patient outcomes following DBS.
未标注
帕金森病（PD）与认知和人格变化有关，这些变化超出了其典型的运动症状。
目的
分析丘脑底核深部脑刺激（STN-DBS）对帕金森病患者执行功能（EF）和人格（五因素模型-FFM）的影响，比较单纯药物治疗患者与接受药物和STN-DBS联合治疗患者的结果。
方法
共69名参与者分为三组：DBS组、药物治疗组和对照组。评估包括量表、测试和评定量表，结果汇总在表格中，突出社会人口统计学变量和筛查结果。
结果
认知评估表明，与药物治疗组相比，DBS组的认知得分略低。人格差异最小，仅外向性有显著差异。
结论
STN-DBS对帕金森病患者的执行功能或人格特质没有显著影响。这些结果凸显了在评估DBS治疗后患者结果时考虑更广泛的认知和神经精神因素的重要性。
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