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在卢布尔雅那大学医学中心实施用于治疗恶性或癌前胰腺肿瘤患者的机器人手术平台。

The implementation of a robotic surgical platform for the treatment of patients with malignant or pre-malignant pancreatic tumors at the University Medical Center Ljubljana.

作者信息

Petric Miha, Polanco Patricio Marcelo, Grosek Jan, Tomazic Ales, Trotovsek Blaz, Plesnik Bostjan

机构信息

Department of Abdominal Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia.

Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Radiol Oncol. 2025 Sep 5;59(3):425-434. doi: 10.2478/raon-2025-0051. eCollection 2025 Sep 1.

DOI:10.2478/raon-2025-0051
PMID:40959923
Abstract

BACKGROUND

Robotic platforms are increasingly employed in the field of minimally invasive pancreatic surgery. It is essential to develop an innovative method that ensures both safety and efficacy, producing outcomes comparable to those of established treatment modalities. Implementation process should incorporate surgical science, education, local implementation, and non-technical skills. In our study, we describe the safe implementation of a robotic platform in pancreatic surgery within our medical institution.

PATIENTS AND METHODS

We analysed prospectively collected data from the first ten consecutive robotic-assisted distal pancreatectomies (RDP) and pancreatoduodenectomies (RPD). Due to nature of the study basic statistical analysis were performed.

RESULTS

The mean operating time was 211minutes (±49.4) for RDP and 365 minutes (±69.6) for RPD, with blood loss 330 mL for RDP and 195 mL for RPD. Hospital stay was 8.7 days (±3.9) in RDP and 7.9 days (±3.9) in RPD. One patient (10%) in the RDP group developed clinically relevant postoperative pancreatic fistula (CR-POPF) and delayed gastric emptying (DGE). The mean tumour size was 31 mm (±9.8) in the RDP and 27 mm (±7.5) in the RPD. The mean number of lymph nodes harvested was 6 (0-24) in the RDP and 15 (6-22) in the RPD. The R0 resection rate was 60% in the RDP and 70% in the RPD.

CONCLUSIONS

Robotic surgical technology can be safely and effectively integrated into a clinical setting. This integration should be facilitated through a well-established training program and curriculum. Nonetheless, patient selection is important, especially in the early phases of robotic program development.

摘要

背景

机器人平台在微创胰腺手术领域的应用日益广泛。开发一种既能确保安全性又能保证有效性、产生与既定治疗方式相当结果的创新方法至关重要。实施过程应包括外科学、教育、本地实施和非技术技能。在我们的研究中,我们描述了在我们医疗机构中机器人平台在胰腺手术中的安全实施情况。

患者与方法

我们前瞻性分析了连续进行的前十例机器人辅助远端胰腺切除术(RDP)和胰十二指肠切除术(RPD)的收集数据。由于研究性质,进行了基本的统计分析。

结果

RDP的平均手术时间为211分钟(±49.4),RPD为365分钟(±69.6),RDP的失血量为330毫升,RPD为195毫升。RDP的住院时间为8.7天(±3.9),RPD为7.9天(±3.9)。RDP组有1例患者(10%)发生了临床相关的术后胰瘘(CR-POPF)和胃排空延迟(DGE)。RDP的平均肿瘤大小为31毫米(±9.8),RPD为27毫米(±7.5)。RDP平均切除的淋巴结数量为6个(0 - 24个),RPD为15个(6 - 22个)。RDP的R0切除率为60%,RPD为70%。

结论

机器人手术技术可以安全有效地融入临床环境。这种融入应通过完善的培训计划和课程来促进。尽管如此,患者选择很重要,尤其是在机器人手术项目发展的早期阶段。

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