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玻璃离子水门汀及壳聚糖改性玻璃离子水门汀的力学性能和氟释放曲线评估

Evaluation of the Mechanical Properties and Fluoride Release Profiles of a GIC and Chitosan-modified GIC.

作者信息

Thenumkal Elza, Sahoo Nirupama, Chopra Saroj, Joshi Pooja, Mustafa Mohammed, Kumari Deesha

机构信息

Department of Pediatric and Preventive Dentistry, Mar Baselios Dental College, Kothamangalam, Kerala, India, Phone: +91 9847318911, e-mail:

Department of Periodontology, Kalinga Institute of Dental Sciences (KIDS), Kalinga Institute of Industrial Technology (KIIT) Deemed to be University, Bhubaneswar, Odisha, India.

出版信息

J Contemp Dent Pract. 2025 May 1;26(5):468-472. doi: 10.5005/jp-journals-10024-3844.

Abstract

AIM

To evaluate the effect of addition of 10% v/v and 20% v/v chitosan (CH), a biopolymer, into FUJI IX glass ionomer cement (GIC) on its compressive strength (CS), diametral tensile strength (DTS), and fluoride release (FR) at both 24 hours and 7 days after preparation of the cement mix.

MATERIALS AND METHODS

A total of 60 disc-shaped samples with dimensions 6 mm length and 4 mm diameter for CS ( = 30) evaluation and 3 mm height and 6 mm diameter for DTS ( = 30) evaluation were prepared using Teflon molds. All the samples were divided into three groups, group I: Consisting of FUJI IX GIC ( = 20.), i.e., control; group II: Consisting of 10% v/v CH GIC ( = 20), and group III: Consisting of 20% v/v CH GIC ( = 20). The concentration of cumulative fluoride ion released was determined as function of time using a fluoride ion-selective electrode (ORION) at 24 hours and 7 days. Analysis of variance (ANOVA) and the unpaired ""-test were used to the mean values, and then, at a significance threshold of 5%, Tukey's honestly significant difference analysis was performed.

RESULTS

The highest CS was shown by group II, which being 178.14 ± 4.32 followed by group III with a mean of 154.26 ± 1.86 and 148.16 ± 2.95 for group I. The maximum mean value for DTS was shown by group II, i.e., 16.40 ± 2.29, followed by group III which showed 14.35 ± 1.69, and the least mean value was shown by group I, i.e., 9.12 ± 0.81. Group II showed the highest concentration of release of fluoride at both 24 hours and the 7th day of testing, with the values being 13.09 and 40.59 ppm, respectively. This was followed by group III which showed an FR of 10.61 and 31.13 ppm.

CONCLUSION

On conclusion, it is proven that 10% v/v CH GIC significantly enhanced the CS, DTS, and FR compared with 20% v/v CH GIC and FUJI IX GIC.

CLINICAL SIGNIFICANCE

The condensable GICs, which were created for atraumatic restorative treatment, need more advancement in their mechanical and anticariogenic qualities since they have greater occlusal wear rate and lower fracture strength and antibacterial qualities than other restorative materials. Bioadhesive CH-fluoride microparticles aid in enhanced fluoride availability and absorption, giving protection against caries. How to cite this article: Thenumkal E, Sahoo N, Chopra S, . Evaluation of the Mechanical Properties and Fluoride Release Profiles of a GIC and Chitosan-modified GIC. J Contemp Dent Pract 2025;26(5):468-472.

摘要

目的

评估向富士IX玻璃离子水门汀(GIC)中添加10%(体积/体积)和20%(体积/体积)的生物聚合物壳聚糖(CH)对其抗压强度(CS)、径向拉伸强度(DTS)以及在水门汀混合物制备后24小时和7天时氟释放(FR)的影响。

材料与方法

使用聚四氟乙烯模具制备了总共60个圆盘形样品,其中30个用于CS评估,尺寸为长6毫米、直径4毫米;30个用于DTS评估,尺寸为高3毫米、直径6毫米。所有样品分为三组,第一组:由富士IX GIC组成(n = 20),即对照组;第二组:由10%(体积/体积)CH GIC组成(n = 20),第三组:由20%(体积/体积)CH GIC组成(n = 20)。使用氟离子选择性电极(ORION)在24小时和7天时测定累积释放的氟离子浓度随时间的变化。采用方差分析(ANOVA)和不成对t检验分析平均值,然后在5%的显著性阈值下进行Tukey's真实显著性差异分析。

结果

第二组显示出最高的CS,为178.14±4.32,其次是第三组,平均值为154.26±1.86,第一组为148.16±2.95。第二组显示出DTS的最大平均值,即16.40±2.29,其次是第三组,为14.35±1.69,第一组显示的平均值最小,即9.12±0.81。第二组在测试的24小时和第7天均显示出最高的氟释放浓度,值分别为13.09和40.59 ppm。其次是第三组,其氟释放量为10.61和31.13 ppm。

结论

总之,已证明10%(体积/体积)CH GIC与20%(体积/体积)CH GIC和富士IX GIC相比,显著提高了CS、DTS和FR。

临床意义

为非创伤性修复治疗而研发的可凝结GIC,由于其咬合磨损率更高、断裂强度和抗菌性能低于其他修复材料,因此在机械性能和抗龋性能方面需要进一步改进。生物粘附性CH-氟微粒有助于提高氟的有效性和吸收,提供防龋保护。如何引用本文:Thenumkal E,Sahoo N,Chopra S等。GIC和壳聚糖改性GIC的力学性能和氟释放曲线评估。《当代牙科实践杂志》2025;26(5):468 - 472。

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