Hourston George J M, Chan Julia J, Cooper Haydn, Quinn Kate R, Parker Martyn
Department of Trauma and Orthopaedic Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Department of Trauma and Orthopaedic Surgery, Peterborough City Hospital, Peterborough, United Kingdom.
Eur J Orthop Surg Traumatol. 2025 Sep 17;35(1):399. doi: 10.1007/s00590-025-04521-z.
Hip fracture patients require perioperative optimisation, often including blood transfusion. In this study, we sought to evaluate whether admission haemoglobin level or perioperative transfusion differs among patients admitted with intracapsular or extracapsular hip fractures, and whether this practice has evolved over 32 years in our unit.
We performed a retrospective analysis of data collected prospectively for all hip fracture patients, January 1989-August 2021. Exclusion criteria were age < 60 years, pathological hip fractures or surgical treatment other than fixation for extracapsular fracture or hemiarthroplasty for intracapsular fracture. We collated demographic data, admission haemoglobin, hours to surgery and perioperative blood transfusion records. Chi-squared tests and t-tests were utilised to compare these data between fracture types, and a multivariable logistic regression analysis was performed.
A total of 12,166 patients were screened from our internal database, and 8578 patients met the inclusion criteria (3928 intracapsular hip fractures, 4603 extracapsular hip fractures). 76.3% (6544) were female. Patients admitted with intracapsular fractures had significantly higher haemoglobin on admission than those with extracapsular fractures (124.5 g/L vs. 119.4 g/L, p < 0.001). Preoperative and intraoperative transfusion requirements were lower for intracapsular fractures, with 15.5% (609/3928) requiring perioperative transfusion compared with 37.7% (1736/4603) of extracapsular fracture patients (p < 0.001). Time to surgery was similar between groups (28.37 h vs. 28.02 h, p = 0.548). Over the study period, transfusion has declined each year (intracapsular R = 0.568, p < 0.001; extracapsular R = 0.840, p < 0.001). Multivariable regression analysis highlighted increasing age, lower admission haemoglobin, extracapsular fracture, and intramedullary nailing for extracapsular fracture as risk factors for perioperative transfusion.
We demonstrate that individuals with intracapsular hip fractures generally present with higher admission haemoglobin concentration and require fewer blood transfusions compared to those with extracapsular fractures. Over 32 years, our overall transfusion rate has declined, reflecting evolving surgical techniques and updated transfusion protocols.
髋部骨折患者需要围手术期优化,通常包括输血。在本研究中,我们试图评估囊内或囊外髋部骨折患者入院时的血红蛋白水平或围手术期输血情况是否存在差异,以及这种做法在我们科室32年里是否有所变化。
我们对1989年1月至2021年8月期间前瞻性收集的所有髋部骨折患者的数据进行了回顾性分析。排除标准为年龄<60岁、病理性髋部骨折或除囊外骨折固定术或囊内骨折半关节置换术以外的手术治疗。我们整理了人口统计学数据、入院时血红蛋白、手术时间和围手术期输血记录。采用卡方检验和t检验比较骨折类型之间的这些数据,并进行多变量逻辑回归分析。
从我们的内部数据库中总共筛选出12166例患者,8578例患者符合纳入标准(3928例囊内髋部骨折,4603例囊外髋部骨折)。76.3%(6544例)为女性。囊内骨折患者入院时的血红蛋白水平显著高于囊外骨折患者(124.5g/L对119.4g/L,p<0.001)。囊内骨折的术前和术中输血需求较低,15.5%(609/3928)的患者需要围手术期输血,而囊外骨折患者为37.7%(1736/4603)(p<0.001)。两组之间的手术时间相似(28.37小时对28.02小时,p=0.548)。在研究期间,输血率逐年下降(囊内R=0.568,p<0.001;囊外R=0.840,p<0.001)。多变量回归分析强调年龄增加、入院时血红蛋白水平降低、囊外骨折以及囊外骨折髓内钉固定术是围手术期输血的危险因素。
我们证明,与囊外骨折患者相比,囊内髋部骨折患者入院时的血红蛋白浓度通常较高,输血需求较少。在32年里,我们的总体输血率有所下降,这反映了手术技术的发展和输血方案的更新。