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德意志联邦共和国石棉水泥行业员工减少情况的流行病学调查。

Epidemiological investigations of decreased employees of the asbestos cement industry in the Federal Republic of Germany.

作者信息

Beck E G, Schmidt P

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B. 1985 Dec;181(3-5):207-15.

PMID:4096142
Abstract

An epidemiological study of the causes of death was performed covering the entire German asbestos cement industry (10 plants). Of 376 workers who had died in the period of 1 January 1976 - 31 December 1980 and who had been employed for a minimum of 10 years, 314 were included; 307 of these were men. Special consideration was given to the asbestos-related diseases asbestosis, asbestosis in combination with lung cancer, and mesothelioma of the pleura or peritoneum. The relationship between lung cancer with asbestosis and lung cancer without asbestosis is nearly 1:1. From this the conclusion can be drawn that a causal relationship between asbestos exposure and lung cancer can be assumed in only half of the lung cancer cases. This is, however, an upper approximation, since 15 cases of lung cancer were found which is 1/3 less than the expected number in comparison with the normal population. This documents the relatively small excess (SPMR = 1.2) of all cases of lung cancer detected in the asbestos cement industry as compared to the expected lung cancer cases not due to asbestos.

摘要

对整个德国石棉水泥行业(10家工厂)进行了一项死亡原因的流行病学研究。在1976年1月1日至1980年12月31日期间死亡且至少工作了10年的376名工人中,314人被纳入研究;其中307人为男性。特别关注了与石棉相关的疾病,如石棉肺、石棉肺合并肺癌以及胸膜或腹膜间皮瘤。有石棉肺的肺癌与无石棉肺的肺癌之间的关系几乎为1:1。由此可以得出结论,在仅一半的肺癌病例中可以假定石棉暴露与肺癌之间存在因果关系。然而,这是一个上限近似值,因为发现了15例肺癌病例,与正常人群相比,比预期数量少了1/3。这证明与非石棉所致预期肺癌病例相比,在石棉水泥行业检测到的所有肺癌病例的相对超额数较小(标准化死亡比=1.2)。

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