Wanger P, Persson H E
Acta Ophthalmol (Copenh). 1985 Dec;63(6):716-20. doi: 10.1111/j.1755-3768.1985.tb01588.x.
The present study was undertaken in order to find out whether electroretinographic examinations could reveal signs of functional abnormalities before morphological changes are detected in the diabetic retina. Pattern-reversal and flash electroretinograms (ERG) and oscillatory potentials (OP) were recorded in 24 diabetics and 10 age-matched normal controls. The diabetic group consisted of 11 patients without retinopathy and 13 patients with background retinopathy. No significant changes in pattern-reversal or flash ERG or OP amplitudes were observed in the diabetic group with normal fundus or with background retinopathy. The findings imply that ERG examination with the described techniques does not reveal retinal dysfunction in diabetics before retinopathy can be detected by means of retinal biomicroscopy.
本研究旨在探讨在糖尿病视网膜出现形态学改变之前，视网膜电图检查是否能够揭示功能异常的迹象。对24例糖尿病患者和10例年龄匹配的正常对照者进行了图形翻转视网膜电图（ERG）、闪光视网膜电图（ERG）及振荡电位（OP）记录。糖尿病组包括11例无视网膜病变患者和13例有背景性视网膜病变患者。在眼底正常或有背景性视网膜病变的糖尿病组中，未观察到图形翻转或闪光ERG及OP波幅有显著变化。这些发现表明，采用所述技术进行的ERG检查在通过视网膜生物显微镜检测到视网膜病变之前，无法揭示糖尿病患者的视网膜功能障碍。
