Zhou Tongliang, Utecht-Jarzyńska Greta, Szostak Michal
Department of Chemistry, Rutgers University, 73 Warren Street, Newark, NJ 07102, United States.
University of Lodz, Faculty of Chemistry, Tamka 12, 91403 Łódź, Poland.
Coord Chem Rev. 2024 Aug 1;512. doi: 10.1016/j.ccr.2024.215867. Epub 2024 Apr 26.
In the past two decades, NHCs (NHC = N-heterocyclic carbenes) have emerged as one of the most important classes of ligands in transition metal catalysis. Although historically 5-membered carbenes, such as imidazol-2-ylidenes, have been the dominant class of NHC ligands in transition metal catalysis, recently, ring expanded carbenes on 6-, 7-, 8-, 9- and 10-membered ring systems have been shown to provide significant advantages in numerous catalytic reactions embracing various metals, transformations and mechanisms. In this comprehensive review, we provide a survey of the applications of ring-expanded N-heterocyclic carbenes (reNHCs) in transition metal catalysis. Spanning from the initial reports on ring-expanded NHCs through June 2023, the review centers on the types of ring-expanded NHCs, their organometallic complexes and applications in catalytic processes. By delving into the impact of ring-expanded NHC ligands, the review aims to provide the reader with an understanding of the significance of this ligand class and its pivotal role in transition metal catalysis and organometallic chemistry.
在过去二十年中，N-杂环卡宾（NHC = N-杂环卡宾）已成为过渡金属催化中最重要的配体类别之一。尽管从历史上看，五元卡宾，如咪唑-2-亚基，一直是过渡金属催化中NHC配体的主要类别，但最近，六元、七元、八元、九元和十元环体系上的扩环卡宾已被证明在涉及各种金属、转化和机理的众多催化反应中具有显著优势。在这篇综述中，我们对扩环N-杂环卡宾（reNHC）在过渡金属催化中的应用进行了概述。涵盖从关于扩环NHC的最初报道到2023年6月，该综述聚焦于扩环NHC的类型、它们的有机金属配合物以及在催化过程中的应用。通过深入探讨扩环NHC配体的影响，该综述旨在让读者了解这类配体的重要性及其在过渡金属催化和有机金属化学中的关键作用。
