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通过超微结构细胞化学对前黑素小体中的碳水化合物进行显示。

Demonstration of carbohydrates in premelanosomes by ultrastructural cytochemistry.

作者信息

Sahlmann B, Rathjen P, Stanka P

出版信息

Arch Dermatol Res. 1985;278(2):148-52. doi: 10.1007/BF00409222.

DOI:10.1007/BF00409222
PMID:4096541
Abstract

The framework for melanin synthesis in the interior of the premelanosomes - the matrix - was subjected to ultrastructural cytochemical examination in cells of the retinal pigment epithelium of chick embryos, in melanocytes of rat skin, and in melanocytes and nevus cells of human skin. The positive results obtained using the silver methods of Thiéry and Rambourg indicated the presence of carbohydrates in the matrix of the premelanosomes.

摘要

在鸡胚视网膜色素上皮细胞、大鼠皮肤黑素细胞以及人类皮肤黑素细胞和痣细胞中,对前黑素小体内部(即基质)的黑色素合成框架进行了超微结构细胞化学检查。使用蒂埃里和兰布尔的银染方法所获得的阳性结果表明,前黑素小体基质中存在碳水化合物。

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引用本文的文献

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本文引用的文献

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The distribution of glycogen and lipids in human skin.糖原和脂质在人体皮肤中的分布。
J Invest Dermatol. 1951 Sep;17(3):147-57. doi: 10.1038/jid.1951.75.
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MACROMOLECULAR CHANGES IN PIGMENTARY DISORDERS.色素紊乱中的大分子变化
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The induction and ultrastructural study of amelanotic dermal melanocytoma in the Syrian albino hamster.叙利亚白化仓鼠无色素性皮肤黑素细胞瘤的诱导及超微结构研究
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Evidence of membrane transformation during melanogenesis. Electron microscopic study on the retinal pigment epithelium of chick embryos.黑色素生成过程中膜转化的证据。鸡胚视网膜色素上皮的电子显微镜研究。
Cell Tissue Res. 1981;214(2):343-53. doi: 10.1007/BF00249216.
7
Observations on the structure of the eumelanosome matrix in melanosomes of the chick retinal pigment epithelium.
Anat Rec. 1981 Aug;200(4):415-20. doi: 10.1002/ar.1092000404.
8
Characterization of structural properties for morphological differentiation of melanosomes: II. Electron microscopic and SDS-PAGE comparison of melanosomal matrix proteins in B16 and Harding Passey melanomas.黑素小体形态分化的结构特性表征:II. B16和哈丁·帕西黑色素瘤中黑素小体基质蛋白的电子显微镜和SDS-PAGE比较
J Invest Dermatol. 1982 Jan;78(1):76-81. doi: 10.1111/1523-1747.ep12497959.
9
The influence of embedding media and fixation on the post-embedment ultrastructural demonstration of complex carbohydrates. I. Morphology and periodic acid-thiocarbohydrazide-silver proteinate staining of vicinal diols.包埋介质和固定对复合碳水化合物包埋后超微结构显示的影响。I. 邻二醇的形态学及高碘酸-硫代碳酰肼-蛋白银染色
Histochem J. 1983 Aug;15(8):763-84. doi: 10.1007/BF01003340.
10
Selective aberration and pigment loss in melanosomes of malignant melanoma cells in vitro by glycosylation inhibitors: premelanosomes as glycoprotein.体外糖基化抑制剂对恶性黑色素瘤细胞黑素小体的选择性畸变和色素丢失:前黑素小体作为糖蛋白
J Invest Dermatol. 1983 Aug;81(2):106-14. doi: 10.1111/1523-1747.ep12542192.