Kida Masahiko Y, Imaizumi Mitsuyoshi, Yamamoto Toshiyuki
Division of Internal Medicine, Fukushima Jukokai Hospital, 1-40, Kita-machi, Fukushima, 960-8102, Japan.
Department of Otolaryngology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
Dysphagia. 2025 Sep 18. doi: 10.1007/s00455-025-10889-1.
The risk of aspiration pneumonia has been reported to increase with age, especially in frail elderly patients with cerebrovascular and/or neurodegenerative disorders. To prevent this type of pneumonia, aspiration prevention surgery (APS) procedures have been demonstrated to be effective. However, the comprehensive efficacy of APS, not only in terms of survival rates, but also in terms of medical costs and caregiver burden, has not been fully evaluated in elderly patients requiring aspiration care. Thus, the aim of the current study was to demonstrate the validity of APS in elderly patients with cerebrovascular or neurodegenerative disorders. A total of 135 patients were enrolled; 82 with cerebrovascular disorders and 53 with neurodegenerative disorders, in whom APS was applied to 52 and 36 patients, respectively. The 2-year survival rates, medical costs, and number of suctioning procedures as a measure of caregiver burden were investigated in patients treated with APS (the APS group) and those without APS (the non-APS group). The 2-year survival rates for all patients were 53.4% in the APS group and 4.3% in the non-APS group. This result showed significantly better outcomes in the APS group. Moreover, in the APS group, the postoperative suction frequency showed a significant decrease compared to the preoperative suction frequency. Finally, medical costs were significantly lower in the APS group compared to the non-APS group. The results of this study demonstrate that APS contributed to improved survival rates, reduced medical costs, and a decrease in suctioning frequency in elderly patients with cerebrovascular or neurodegenerative diseases.
据报道,误吸性肺炎的风险会随着年龄增长而增加,尤其是在患有脑血管疾病和/或神经退行性疾病的体弱老年患者中。为预防此类肺炎,已证明误吸预防手术(APS)程序是有效的。然而,对于需要误吸护理的老年患者,APS的综合疗效,不仅在生存率方面,而且在医疗成本和护理负担方面,尚未得到充分评估。因此,本研究的目的是证明APS在患有脑血管疾病或神经退行性疾病的老年患者中的有效性。总共招募了135名患者;其中82名患有脑血管疾病,53名患有神经退行性疾病,分别对52名和36名患者实施了APS。对接受APS治疗的患者(APS组)和未接受APS治疗的患者(非APS组)的2年生存率、医疗成本以及作为护理负担衡量指标的吸痰程序次数进行了调查。所有患者的2年生存率在APS组为53.4%,在非APS组为4.3%。这一结果表明APS组的预后明显更好。此外,在APS组中,术后吸痰频率与术前吸痰频率相比显著降低。最后,APS组的医疗成本明显低于非APS组。本研究结果表明,APS有助于提高患有脑血管或神经退行性疾病的老年患者的生存率、降低医疗成本并减少吸痰频率。