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Bempedoic Acid and the Uric Acid Paradox: Reflections on the Recent Meta-analysis.

作者信息

Bonanni Luca, Ferri Nicola

机构信息

Department of Medicine, Ospedale Dell'Angelo, Venice, Italy.

Department of Medicine, University of Padova, Padova, Italy.

出版信息

Cardiovasc Drugs Ther. 2025 Sep 18. doi: 10.1007/s10557-025-07781-3.

DOI:10.1007/s10557-025-07781-3
PMID:40965761
Abstract
摘要

相似文献

1
Bempedoic Acid and the Uric Acid Paradox: Reflections on the Recent Meta-analysis.
Cardiovasc Drugs Ther. 2025 Sep 18. doi: 10.1007/s10557-025-07781-3.
2
Evaluating the effects of bempedoic acid on lipid profiles and cardiovascular risk: An umbrella review of meta-analyses.评估贝派地酸对血脂谱和心血管风险的影响：一项荟萃分析的伞状综述
Qatar Med J. 2025 Jul 5;2025(2):51. doi: 10.5339/qmj.2025.51. eCollection 2025.
3
Three months of bempedoic acid treatment does not affect cystatin C-based estimation of glomerular filtration rate.三个月的贝派地酸治疗不影响基于胱抑素C的肾小球滤过率估算。
High Blood Press Cardiovasc Prev. 2025 Sep;32(5):533-541. doi: 10.1007/s40292-025-00732-x. Epub 2025 Aug 2.
4
Impact of Bempedoic acid on LDL-C reduction and cardiovascular outcomes: A comprehensive meta-analysis of randomized controlled trials.贝前列素酸对 LDL-C 降低和心血管结局的影响：随机对照试验的综合荟萃分析。
Curr Probl Cardiol. 2024 Feb;49(2):102191. doi: 10.1016/j.cpcardiol.2023.102191. Epub 2023 Nov 17.
5
Risk of cardiovascular outcomes with bempedoic acid in high-risk statin intolerant patients: a systematic review and meta analysis.高危他汀不耐受患者使用苯扎贝特酸的心血管结局风险：系统评价和荟萃分析。
Future Cardiol. 2024;20(11-12):639-650. doi: 10.1080/14796678.2024.2388478. Epub 2024 Aug 14.
6
Efficacy and safety of bempedoic acid lipid-lowering therapy: a systematic review and meta-analysis of randomized controlled trials.贝匹地酸降脂治疗的疗效和安全性：随机对照试验的系统评价和荟萃分析。
Eur J Clin Pharmacol. 2023 Nov;79(11):1453-1463. doi: 10.1007/s00228-023-03555-8. Epub 2023 Sep 6.
7
Cost-Effectiveness of Bempedoic Acid in High Cardiovascular Risk Patients with Statin Intolerance: An Analysis of the CLEAR Outcomes Trial.贝派地酸在他汀类药物不耐受的高心血管风险患者中的成本效益：CLEAR Outcomes试验分析
Am J Cardiovasc Drugs. 2025 Aug 20. doi: 10.1007/s40256-025-00753-w.
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Effects of bempedoic acid on markers of inflammation and Lp(a).贝匹地酸对炎症标志物和 Lp(a)的影响。
Curr Opin Cardiol. 2024 Jul 1;39(4):280-285. doi: 10.1097/HCO.0000000000001137. Epub 2024 Mar 4.
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Effect of Probiotics on Uric Acid Levels: Meta-Analysis with Subgroup Analysis and Meta-Regression.益生菌对尿酸水平的影响：亚组分析和Meta回归的Meta分析
Nutrients. 2025 Jul 29;17(15):2467. doi: 10.3390/nu17152467.
10
Effect of Bempedoic Acid on Serum Uric Acid and Related Outcomes: A Systematic Review and Meta-analysis of the available Phase 2 and Phase 3 Clinical Studies.贝匹地酸对血清尿酸及相关结局的影响：现有 2 期和 3 期临床研究的系统评价和荟萃分析。
Drug Saf. 2020 Aug;43(8):727-736. doi: 10.1007/s40264-020-00931-6.

本文引用的文献

1
The Clinical Efficacy and Safety of Bempedoic Acid in Patients at Elevated Risk of Cardiovascular Disease: A Meta-Analysis of Randomized Clinical Trials.贝派地酸在心血管疾病高危患者中的临床疗效与安全性：一项随机临床试验的荟萃分析
Cardiovasc Drugs Ther. 2024 Dec;38(6):1415-1420. doi: 10.1007/s10557-023-07474-9. Epub 2023 Jun 1.
2
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients.贝匹地酸在他汀类药物不耐受患者中的心血管结局。
N Engl J Med. 2023 Apr 13;388(15):1353-1364. doi: 10.1056/NEJMoa2215024. Epub 2023 Mar 4.
3
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol.
贝匹地酸降低 LDL 胆固醇的安全性和有效性。
N Engl J Med. 2019 Mar 14;380(11):1022-1032. doi: 10.1056/NEJMoa1803917.