Lakhani Anisa, McElhanon Barbara, He Zhulin, Raol Nikhila, Sharp William G, Karpen Heidi
Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Department of Otolaryngology-Head and Neck Surgery and Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.
J Perinatol. 2025 Sep 18. doi: 10.1038/s41372-025-02422-x.
To evaluate feeding outcomes in preterm infants discharged with feeding tubes (FT).
Retrospective study comparing infants ≤30 weeks gestational age discharged with a nasogastric tube (NGT) or surgically placed feeding tube (spFT) from 2012-2020. The primary outcome was feeding status at 12 months corrected age, defined as full oral feeds (FOF) or feeding tube dependence (FTD) if ongoing FT use.
217 infants were included: 130 discharged with an NGT (60%), 87 with spFT (40%). More NGT infants achieved FOF (NGT = 76%, spFT=24%, p < 0.001). FTD was associated with small for gestational age (aOR= 2.75, p = 0.034), severe bronchopulmonary dysplasia (aOR= 2.36, p = 0.029), and continuous feeds (aOR= 4.06, p < 0.001). Increased oral intake at discharge decreased FTD odds (aOR=0.74, p = 0.010). Infants with spFT had higher healthcare utilization for FT complications (spFT=60%, NGT = 19%, p < 0.001).
These findings can guide FT selection and optimize follow-up for infants at risk of FTD.
评估经鼻饲管（FT）出院的早产儿的喂养结局。
回顾性研究，比较2012年至2020年胎龄≤30周经鼻胃管（NGT）或手术置入饲管（spFT）出院的婴儿。主要结局为矫正年龄12个月时的喂养状况，定义为完全经口喂养（FOF），若仍在使用饲管则为饲管依赖（FTD）。
纳入217例婴儿：130例经NGT出院（60%），87例经spFT出院（40%）。更多经NGT的婴儿实现了FOF（NGT = 76%，spFT = 24%，p < 0.001）。FTD与小于胎龄儿（调整后比值比[aOR]= 2.75，p = 0.034）、重度支气管肺发育不良（aOR = 2.36，p = 0.029）及持续喂养（aOR = 4.06，p < 0.001）相关。出院时经口摄入量增加降低了FTD几率（aOR = 0.74，p = 0.010）。经spFT的婴儿因饲管并发症的医疗资源利用率更高（spFT = 60%，NGT = 19%，p < 0.001）。
这些发现可指导饲管选择并优化对有FTD风险婴儿的随访。
