Kashyap Aparajita, Aziz Maryam, Sun Tony Y, Gorman Sharon Lipsky, Opoku-Anane Jessica, Elhadad Noémie
Columbia University Irving Medical Center, Department of Biomedical Informatics, New York, NY, USA.
Columbia University, Department of Computer Science, New York, NY, USA.
NPJ Womens Health. 2025;3. doi: 10.1038/s44294-025-00053-3. Epub 2025 Jan 30.
We assess racial disparities in medication prescription patterns for endometriosis patients across Medicaid administrative claims data. We use ATC 3 level drug codes to identify drug classes prescribed significantly more frequently for endometriosis patients than a comparison cohort of non-endometriosis patients. Temporal prevalence differences of prescriptions (pre- vs. post-diagnosis) were also examined. The endometriosis cohort comprised 16,372 endometriosis patients (23.3% Black, 66.0% White). Of the 28 drug classes examined, 17 were prescribed significantly less in Black patients and 4 were prescribed significantly more in Black patients. Of the 17 drugs prescribed more often in White patients, 13 have larger disparities pre-diagnosis than post-diagnosis. In the non-endometriosis cohort ( = 3,663,904), 21 drug classes were prescribed significantly more in White patients and 6 were prescribed significantly more in Black patients. Our analysis identifies disparities in prescriptions practices between White and Black endometriosis patients, notably in pain management and comorbidity treatment.
我们通过医疗补助管理索赔数据评估子宫内膜异位症患者药物处方模式中的种族差异。我们使用解剖学治疗学及化学分类系统（ATC）3级药物代码来识别子宫内膜异位症患者比非子宫内膜异位症患者对照队列更频繁开具的药物类别。还检查了处方的时间流行差异（诊断前与诊断后）。子宫内膜异位症队列包括16372名子宫内膜异位症患者（23.3%为黑人，66.0%为白人）。在所检查的28种药物类别中，17种在黑人患者中开具的显著较少，4种在黑人患者中开具的显著较多。在白人患者中更常开具的17种药物中，13种在诊断前的差异比诊断后更大。在非子宫内膜异位症队列（n = 3663904）中，21种药物类别在白人患者中开具的显著更多，6种在黑人患者中开具的显著更多。我们的分析确定了白人和黑人子宫内膜异位症患者在处方实践中的差异，特别是在疼痛管理和合并症治疗方面。
