Missmer Stacey A, Tu Frank F, Agarwal Sanjay K, Chapron Charles, Soliman Ahmed M, Chiuve Stephanie, Eichner Samantha, Flores-Caldera Idhaliz, Horne Andrew W, Kimball Alexandra B, Laufer Marc R, Leyland Nicholas, Singh Sukhbir S, Taylor Hugh S, As-Sanie Sawsan
Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, Grand Rapids, MI, USA.
Department of Obstetrics and Gynecology, NorthShore University Health System, Evanston, IL, USA.
Int J Gen Med. 2021 Jan 7;14:9-25. doi: 10.2147/IJGM.S261139. eCollection 2021.
Endometriosis may exert a profound negative influence on the lives of individuals with the disorder, adversely affecting quality of life, participation in daily and social activities, physical and sexual functioning, relationships, educational and work productivity, mental health, and well-being. Over the course of a lifetime, these daily challenges may translate into limitations in achieving life goals such as pursuing or completing educational opportunities; making career choices or advancing in a chosen career; forming stable, fulfilling relationships; or starting a family, all of which ultimately alter one's life trajectory. The potential for endometriosis to impact the life course is considerable, as symptom onset generally occurs at a time of life (menarche through menopause, adolescence through middle age) when multiple life-changing and trajectory-defining decisions are made. Using a life-course approach, we examine how the known effects of endometriosis on life-domain satisfaction may impact health and well-being across the life course of affected individuals. We provide a quasi-systematic, narrative review of the literature as well as expert opinion on recommendations for clinical management and future research directions.
子宫内膜异位症可能会对患有该疾病的个体的生活产生深远的负面影响，对生活质量、参与日常和社会活动、身体和性功能、人际关系、教育和工作生产力、心理健康及幸福感都有不利影响。在一生当中，这些日常挑战可能会转化为实现生活目标的限制，比如追求或完成教育机会；做出职业选择或在所选择的职业中取得进展；建立稳定、充实的人际关系；或者组建家庭，所有这些最终都会改变一个人的人生轨迹。子宫内膜异位症影响人生历程的可能性相当大，因为症状通常在人生的某个阶段（从初潮到绝经，从青春期到中年）出现，而在这个阶段会做出多个改变人生和决定人生轨迹的决策。我们采用人生历程方法，研究子宫内膜异位症对生活领域满意度的已知影响如何在受影响个体的整个人生历程中影响健康和幸福感。我们对文献进行了准系统的叙述性综述，并提供了关于临床管理建议和未来研究方向的专家意见。
