Li Junfan, Feng Songqi, Wang Yao, Li Chao, Li Peng, Zhang Lijie, Dai Yingxue, Tan Kaike, Wang Liang
Department of Infectious Disease Control and Prevention, Chengdu Center for Disease Control and Prevention, Chengdu, China.
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Front Med (Lausanne). 2025 Sep 3;12:1623909. doi: 10.3389/fmed.2025.1623909. eCollection 2025.
causes Primary Amoebic Meningoencephalitis (PAM), an unusual but fatal disease. Swimming in wild freshwater is commonly regarded as the primary cause of infection. In April, 2024, we discovered a case of PAM in a child, suspected to have contracted the infection through an uncommon route: indoor swimming. This article describes the field epidemiological investigation process, the reasoning behind the speculation of the infection origin, and recommendations for minimizing potential risks.
Face-to-face visit was conducted with the guardian of the case. Field investigations were carried out at suspected venues of infection. Reasonable inferences were made by combining literature and investigation results.
The case manifested typical PAM symptoms, followed by death 7 days after onset. The suspected exposure period was between March 4 and April 3, associated with several instances of swimming in two indoor pools. A field investigation at N Aquatic Center revealed improper disinfection methods, substandard water quality, and a suitable environment for .
N Aquatic Center is the most likely source of infection after synthesizing epidemiological history, field investigation, and laboratory results. Individuals can get infected even when swimming indoors if the water is not well managed. Inspecting, monitoring, and disinfecting pool water should be strengthened.
原发性阿米巴脑膜脑炎（PAM）是一种罕见但致命的疾病。在野生淡水中游泳通常被认为是感染的主要原因。2024年4月，我们发现一名儿童患有PAM，怀疑是通过一种不常见的途径感染的：室内游泳。本文描述了现场流行病学调查过程、对感染源推测的推理以及降低潜在风险的建议。
与病例监护人进行面对面访谈。在疑似感染场所进行现场调查。结合文献和调查结果进行合理推断。
该病例表现出典型的PAM症状，发病7天后死亡。疑似暴露期为3月4日至4月3日，与在两个室内游泳池游泳的几次情况有关。对N水上中心的现场调查发现消毒方法不当、水质不合格以及适合[病原体名称未完整给出]生存的环境。
综合流行病学史、现场调查和实验室结果后，N水上中心是最有可能的感染源。如果水管理不善，即使在室内游泳，个人也可能被感染。应加强对泳池水的检查、监测和消毒。
