瑞典阴茎癌国家指南。
The Swedish national guidelines on penile cancer.
作者信息
Gerdtsson Axel, Abedi Eliya, Baseckas Gediminas, Brorson Håkan, Dorofte Luiza, Fall Sofia, Filipsson Emelie, Forssell Johan, Glombik Dominik, Grelaud Diane, Hellman Fatou, Jakobsson Anna-Karin, Kohestani Kimia, Kristiansen Sinja, Magnusson Jenny, Nilsson Kajsa, Nordlund Per, Persson Erik, Psarias Theodoros, Skeppner Elisabeth, Trägårdh Elin, Ulvskog Emma, Warnolf Åsa, Öfverholm Elisabeth, Kirrander Peter
机构信息
Department of Urology, Skåne University Hospital, Malmö, Sweden; Department of Translational Medicine, Lund University, Sweden; Division of Urology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden; Academic Primary Health Care Centre, Region Stockholm, Stockholm, Sweden.
出版信息
Scand J Urol. 2025 Sep 19;60:189-194. doi: 10.2340/sju.v60.44463.
OBJECTIVE
The Swedish national guidelines on penile cancer were first published in 2013. The objective of the present study is to present the 2023 update of these guidelines and highlight the differences to the European Association of Urology (EAU) / American Association of Clinical Oncology (ASCO) guidelines on penile cancer.
MATERIAL AND METHODS
A review of the literature and a comparison to the EAU / ASCO guideline on penile cancer was performed. Differences between the EAU / ASCO guidelines and the Swedish national guidelines are highlighted. Results: The Swedish national guidelines on penile cancer emphasized the consultation of a national multidisciplinary treatment conference for all patients diagnosed with both primary and recurrent penile cancer or penile intraepithelial neoplasia (PeIN). Clinically lymph node negative patients diagnosed with >pT1G1 are offered dynamic sentinel node biopsy (DSNB). In the EAU / ASCO guidelines the DSNB is optional for T1aG2 patients. Penile cancer surgery is centralized to two hospitals. Perioperative chemotherapy is offered to patients with ≥N2. In the EAU / ASCO guidelines the use of perioperative chemotherapy for N2 patients is optional. A structured follow-up program is advocated to find recurrences at an early stage.
CONCLUSIONS
The Swedish national guidelines on penile cancer have been updated and compared to the EAU / ASCO guidelines. The national multidisciplinary treatment conference, centralization of surgery, the use of perioperative chemotherapy and a structured follow-up are the cornerstones of the Swedish national guidelines on penile cancer.
目的
瑞典阴茎癌国家指南于2013年首次发布。本研究的目的是介绍2023年版该指南的更新内容，并突出其与欧洲泌尿外科学会（EAU）/美国临床肿瘤学会（ASCO）阴茎癌指南的差异。
材料与方法
对文献进行综述，并与EAU/ASCO阴茎癌指南进行比较。突出了EAU/ASCO指南与瑞典国家指南之间的差异。
结果
瑞典阴茎癌国家指南强调，对于所有诊断为原发性和复发性阴茎癌或阴茎上皮内瘤变（PeIN）的患者，均应咨询全国多学科治疗会议。对于诊断为>pT1G1的临床淋巴结阴性患者，建议进行动态前哨淋巴结活检（DSNB）。在EAU/ASCO指南中，T1aG2患者的DSNB为可选项。阴茎癌手术集中在两家医院进行。对于≥N2的患者，提供围手术期化疗。在EAU/ASCO指南中，N2患者使用围手术期化疗为可选项。提倡采用结构化的随访计划，以便早期发现复发。
结论
瑞典阴茎癌国家指南已更新，并与EAU/ASCO指南进行了比较。全国多学科治疗会议、手术集中化、围手术期化疗的使用以及结构化随访是瑞典阴茎癌国家指南的基石。
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