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儿童椎动脉夹层的血管内治疗:病例报告及文献综述

Endovascular treatment of pediatric vertebral artery dissection: Case report and literature review.

作者信息

Zhang Yi, Liao Yujun, Xu Bin, Tian Yanlong, Li Hao

机构信息

Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, 201102, China.

Department of Neurosurgery, Fudan University Huashan Hospital, Shanghai, 200040, China.

出版信息

Int J Surg Case Rep. 2025 Sep 15;136:111935. doi: 10.1016/j.ijscr.2025.111935.

Abstract

INTRODUCTION AND IMPORTANCE

Vertebral artery dissection (VAD) is considered a rare disease in the pediatric population, with challenging to diagnose and treatment. The optimal management remains unclear. Outcome of endovascular treatment, is still rarely reported. Along with a literature review, we aimed to provide information of clinical manifestation, treatment and prognosis in endovascular treatment of pediatric VAD.

PRESENTATION OF CASE

Two endovascular treated cases of spontaneous pediatric VAD were retrospectively reviewed. Clinical symptoms were only headache. Diagnosis was confirmed by DSA. Endovascular coils occlusions of parental vertebral artery were performed in two cases. Both individuals experienced a full recovery, and there were no further occurrences of symptoms or new infarction.

CLINICAL DISCUSSION

VAD is a rare but significant cause of stroke in children. Its incidence in the pediatric population is low, with males being more frequently affected than females. Treatment options for pediatric VAD include conservative medical management, surgical intervention, and endovascular therapy. Endovascular treatment, though less commonly reported, has shown promise in achieving good clinical outcomes with minimal complications. We report two pediatric cases of VAD treated with endovascular therapy. Both patients presented with headache as the primary symptom and achieved full recovery without neurological deficits. Endovascular treatment appears to be a safe and effective option for pediatric VAD, especially in cases where conservative management is insufficient or surgical intervention is not feasible.

CONCLUSIONS

Pediatric VAD is rare and endovascular treatment is feasible for the treatment. More research will still be needed to demonstrate the superiority in clinical outcomes with endovascular therapy.

摘要

引言与重要性

椎动脉夹层(VAD)在儿科人群中被认为是一种罕见疾病,诊断和治疗具有挑战性。最佳治疗方案仍不明确。血管内治疗的结果仍鲜有报道。通过文献综述,我们旨在提供儿科VAD血管内治疗的临床表现、治疗及预后信息。

病例展示

回顾性分析两例接受血管内治疗的儿童自发性VAD病例。临床症状仅为头痛。通过数字减影血管造影(DSA)确诊。两例均采用血管内弹簧圈栓塞患侧椎动脉。两人均完全康复,未再出现症状或新发梗死。

临床讨论

VAD是儿童卒中的罕见但重要病因。其在儿科人群中的发病率较低,男性比女性更易受累。儿科VAD的治疗选择包括保守药物治疗、手术干预和血管内治疗。血管内治疗虽报道较少,但已显示出有望实现良好临床结局且并发症最少。我们报告两例接受血管内治疗的儿科VAD病例。两名患者均以头痛为主要症状,且完全康复,无神经功能缺损。血管内治疗似乎是儿科VAD的一种安全有效的选择,尤其是在保守治疗不足或手术干预不可行的情况下。

结论

儿科VAD罕见,血管内治疗对其治疗可行。仍需更多研究来证明血管内治疗在临床结局方面的优势。

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