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一项比较数字化乳腺摄影、数字化乳腺断层合成及对比增强乳腺摄影既往和新的乳腺剂量测定的多中心研究。

A multicentre study to compare previous and new breast dosimetry for Digital Mammography, Digital Breast Tomosynthesis and Contrast Enhanced Mammography.

作者信息

Soprani Laura, Ravaglia Valentina, Dalmonte Sara, Angelini Lidia, Bassetti Chiara, Scabbio Camilla, Paruccini Nicoletta, Villa Raffaele, De Marco Paolo, Origgi Daniela, Strocchi Sabina, Bortoli Eleonora, Biondi Michelangelo, Cimmino Maria Cristina, Porzio Massimiliano, Cucurachi Noemi, Iacco Martina, Paolucci Massimiliano, Bona Rossana, Angiocchi Maria Chiara, Siciliano Roberto, Bonetti Ilaria, Pagan Laura, Favuzza Virginia, Paulicelli Eleonora, D'Urso Davide, Di Biaso Simona, Pasquali Gabriella, D'Ercole Loredana, Cavallari Monica, Tucciariello Raffaele, Barca Patrizio, Giannelli Marco, Rossetti Veronica, Pierpaoli Elena, Belligotti Eleonora, Cesarini Francesco, Muti Gaia, Piva Virginia, Azzeroni Raffaella, Ardu Veronica, Califano Giorgia, Nicola Emilia Di, Rosasco Raffaella, Maldera Arcangela, Delle Canne Stefania, Quattrocchi Mariagrazia, Cannillo Barbara, Andreatta Paolo, Piai Anna, Castriconi Roberta, Garioni Maria, Bregant Paola, Novellis Sara De, Boschiroli Laura, Sardo Anna

机构信息

Alma Mater Studiorum, Università di Bologna, Italy; AUSL della Romagna, Ravenna, Italy.

AUSL della Romagna, Ravenna, Italy.

出版信息

Phys Med. 2025 Oct;138:105171. doi: 10.1016/j.ejmp.2025.105171. Epub 2025 Sep 19.

DOI:10.1016/j.ejmp.2025.105171
PMID:40974809
Abstract

PURPOSE

The most widely used method in Europe to estimate breast dosimetry in mammography is based on Dance's publications. Recently, AAPM and EFOMP joint Task Group 282 (TG282) has published a new breast dosimetry model, which improves the accuracy in Average Glandular Dose (AGD) estimation. This multicentre study aims to evaluate variations in AGD between conventional and new dosimetry across different modalities and mammography systems.

METHODS

Measurements were conducted on 74 mammography systems from six vendors, installed in hospitals across Italy. Each facility used its own equipment while adhering to the same protocol and spreadsheets. Tube output and Half-Value Layer (HVL) were measured in the two configurations for Digital Mammography (DM), Digital Breast Tomosynthesis (DBT), and Contrast-Enhanced Mammography (CEM). Exposures were performed using a breast-shaped PMMA phantom of different thicknesses. Data were centrally collected to compute AGD using appropriate correction factors for conventional dosimetry and the BreastAGD282 software for TG282 dosimetry, using EU legacy model.

RESULTS

The sample allows for the identification of typical AGD values for both methodologies. The study highlights a reduction in median AGD with the new dosimetry model compared to Dance method across all modalities and vendors. Furthermore, the reduction magnitude depends on x-ray beam quality, modality and compressed breast thickness, ranging from 6.1-8.4 % at 21 mm to 27.3-38.3 % at 90 mm.

CONCLUSIONS

The new TG282 dosimetry model showed a reduction in the estimated median AGD. Notably, the magnitude of this reduction depended on x-ray beam quality, modality and compressed breast thickness.

摘要

目的

欧洲用于估计乳腺钼靶摄影中乳腺剂量测定的最广泛使用的方法基于丹斯的出版物。最近,美国医学物理学会(AAPM)和欧洲医学物理组织(EFOMP)联合任务组282(TG282)发布了一种新的乳腺剂量测定模型,该模型提高了平均腺体剂量(AGD)估计的准确性。这项多中心研究旨在评估不同模式和钼靶摄影系统中传统剂量测定法与新剂量测定法之间AGD的差异。

方法

对安装在意大利各地医院的来自六个供应商的74台钼靶摄影系统进行了测量。每个机构使用自己的设备,同时遵循相同的协议和电子表格。在数字乳腺摄影(DM)、数字乳腺断层合成(DBT)和对比增强乳腺摄影(CEM)的两种配置中测量管输出和半值层(HVL)。使用不同厚度的乳房形状的聚甲基丙烯酸甲酯(PMMA)体模进行曝光。数据集中收集,使用传统剂量测定法的适当校正因子和用于TG282剂量测定法的BreastAGD282软件(使用欧盟传统模型)计算AGD。

结果

该样本有助于确定两种方法的典型AGD值。研究强调,与丹斯方法相比,新剂量测定模型在所有模式和供应商中均使AGD中位数降低。此外,降低幅度取决于X射线束质量、模式和压缩乳房厚度,在21毫米处为6.1 - 8.4%,在90毫米处为27.3 - 38.3%。

结论

新的TG282剂量测定模型显示估计的AGD中位数有所降低。值得注意的是,这种降低的幅度取决于X射线束质量、模式和压缩乳房厚度。

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