人及猪内因子与内因子I型抗体的反应
Reactions of human and hog intrinsic factors with type I antibody to intrinsic factor.
作者信息
Gullberg R
出版信息
Clin Exp Immunol. 1970 Oct;7(4):453-62.
Abstract
A simple and rapid small-scale gel filtration method was applied in studies of type I antibody to intrinsic factor using radioactive vitamin B of high specific activity and purified human and hog intrinsic factor preparations, taking into account the unsaturated B-binding capacity of the individual pernicious anaemia sera. This procedure allows the use of small amounts of reagents. Evidence was obtained for a close antigenic similarity of determinants of human and hog intrinsic factor. The use of purified intrinsic-factor preparations is important.
摘要
考虑到个别恶性贫血血清的不饱和B结合能力，采用一种简单快速的小规模凝胶过滤方法，使用高比活放射性维生素B以及纯化的人源和猪源内因子制剂，对I型内因子抗体进行研究。该方法允许使用少量试剂。已获得证据表明人源和猪源内因子的决定簇具有密切的抗原相似性。使用纯化的内因子制剂很重要。
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引用本文的文献
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Sensitive test for antibody type I to intrinsic factors.
Clin Exp Immunol. 1971 Dec;9(6):833-8.
本文引用的文献
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