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Trichiasis as a clinical manifestation of subconjunctival epithelioid hemangioendothelioma: a rare case report.

作者信息

Hu Mingjue, Wang Jinlin, Zhou Sirui, Chen Yuanyuan, Luo Ting, Guo Juan, Wang Zhanfeng, Sun Yi

机构信息

Department of Ophthalmology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.

Department of Pathology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.

出版信息

Front Oncol. 2025 Sep 4;15:1638365. doi: 10.3389/fonc.2025.1638365. eCollection 2025.

Abstract

Epithelioid hemangioendothelioma(EHE) is a rare, low-grade malignant tumor of vascular endothelial origin, commonly found in the lungs, liver, bones, and soft tissue. However, orbital involvement is uncommon. This study presents a rare case of EHE located in the orbit and confined to the subconjunctival space which has not been previously documented. An elderly male patient presented with a six-month history of discomfort in his left eye, initially diagnosed with lower eyelid trichiasis and scheduled for surgical intervention. A detailed examination identified a purplish, spherical mass beneath the fornix conjunctiva of the left lower eyelid. Computed tomography (CT) imaging of the orbit revealed a well-defined soft tissue mass beneath the left globe, adjacent to the inferior rectus muscle, with no evidence of invasion into the orbital cavity. Ultrasound showed a hypoechoic mass with abundant internal vascularity. Following complete surgical excision, histopathological analysis confirmed the diagnosis of EHE. Postoperative follow-up revealed no signs of recurrence, with full resolution of the trichiasis. No eye movement disorders or visual abnormalities were observed. Despite its generally low malignancy, EHE carries a risk of recurrence and metastasis. Complete excision is crucial to minimize recurrence risk, and long-term follow-up is essential for optimal management.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd0/12443531/88144b99bbf8/fonc-15-1638365-g001.jpg

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