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临床试验机构的集中式每日药物管理及具体实施方案。

Centralized daily drug management in clinical trial institutions and specific implementation plans.

作者信息

Tang Yu, Fang Xiaolong

机构信息

School of Medical, Jiangnan University, Wuxi, China.

Department of General Surgery, The Affiliated Wuxi No. 2 People's Hospital of Jiangnan University, Wuxi, China.

出版信息

Front Drug Saf Regul. 2025 Jun 20;5:1620314. doi: 10.3389/fdsfr.2025.1620314. eCollection 2025.

DOI:10.3389/fdsfr.2025.1620314
PMID:40978505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12443124/
Abstract

BACKGROUND

Experimental drug management is an important part of clinical trial management and directly relates to the reliability of clinical trial data and the safety of participants. This study explores the implementation of centralized pharmacy management in clinical drug trials, addressing the limitations of decentralized approaches.

METHODS

It involves the establishment of a centralized drug warehouse with unified processes and digital systems, primarily relying on the Cold Chain Cloud Platform, Service Cloud Platform, and Enterprise WeChat Platform, to enhance precision and efficiency.

RESULTS

It indicated a significant reduction in error rates and improved adherence to clinical trial protocols. The centralized model also minimized protocol deviations and strengthened participant safety.

CONCLUSION

It highlights the benefits of centralized management in enhancing drug administration efficiency and maintaining high standards of trial conduct, suggesting future integration with Artificial Intelligence (AI) and Electronic Health Records (EHR) for more precise pharmaceutical services.

摘要

背景

试验用药物管理是临床试验管理的重要组成部分，直接关系到临床试验数据的可靠性和参与者的安全。本研究探讨了在临床药物试验中实施集中药房管理，以解决分散式方法的局限性。

方法

它涉及建立一个具有统一流程和数字系统的集中式药品仓库，主要依靠冷链云平台、服务云平台和企业微信平台，以提高精准度和效率。

结果

结果表明错误率显著降低，对临床试验方案的依从性得到改善。集中式模式还将方案偏差降至最低，并加强了参与者的安全。

结论

它突出了集中管理在提高药物管理效率和维持高标准试验实施方面的益处，建议未来与人工智能（AI）和电子健康记录（EHR）整合，以提供更精准的药学服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/7585edcb20eb/fdsfr-05-1620314-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/8f31ffd586cc/fdsfr-05-1620314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/816df2046c78/fdsfr-05-1620314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/559c3b625a14/fdsfr-05-1620314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/186414405451/fdsfr-05-1620314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/7585edcb20eb/fdsfr-05-1620314-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/8f31ffd586cc/fdsfr-05-1620314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/816df2046c78/fdsfr-05-1620314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/559c3b625a14/fdsfr-05-1620314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/186414405451/fdsfr-05-1620314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d45/12443124/7585edcb20eb/fdsfr-05-1620314-g005.jpg

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2
Novel Clinical Trial Designs with Dose Optimization to Improve Long-term Outcomes.具有剂量优化的新型临床试验设计以改善长期结局。
Clin Cancer Res. 2023 Nov 14;29(22):4549-4554. doi: 10.1158/1078-0432.CCR-23-2222.
3
Closed-Loop Medication Management with an Electronic Health Record System in U.S. and Finnish Hospitals.美国和芬兰医院的电子病历系统闭环药物管理。
Int J Environ Res Public Health. 2023 Aug 30;20(17):6680. doi: 10.3390/ijerph20176680.
4
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Ageing Res Rev. 2023 Sep;90:102028. doi: 10.1016/j.arr.2023.102028. Epub 2023 Aug 6.
5
Priority-based replenishment policy for robotic dispensing in central fill pharmacy systems: a simulation-based study.基于优先级的中央供应药房系统机器人配发补货策略：基于模拟的研究。
Health Care Manag Sci. 2023 Jun;26(2):344-362. doi: 10.1007/s10729-023-09630-x. Epub 2023 Mar 11.
6
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7
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8
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9
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JAMA Netw Open. 2022 May 2;5(5):e2211644. doi: 10.1001/jamanetworkopen.2022.11644.
10
Quality problems of clinical trials in China: evidence from quality related studies.中国临床试验的质量问题：来自质量相关研究的证据。
Trials. 2022 Apr 23;23(1):343. doi: 10.1186/s13063-022-06281-1.