V R Balaji, D Manikandan, M D Varshiny
Department of Periodontics & Implant Dentistry, CSI College of Dental Sciences and Research, Madurai, Recognised by Government of India and Dental Council Of India, New Delhi, Affliated to The Tamil Nadu Dr MGR Medical University, Chennai, India.
Bioinformation. 2025 Jun 30;21(6):1683-1688. doi: 10.6026/973206300211683. eCollection 2025.
Mechanical instrumentation of root surfaces results in the formation of a smear layer that may impede the reattachment of connective tissue. Root conditioning agents are employed to remove the smear layer, expose collagen fibres and facilitate improved tissue regeneration. Therefore, it is of interest to assess the efficacy of five root conditioning agents-20% citric acid, 17% EDTA, 37% phosphoric acid, 250 mg/mL tetracycline hydrochloride and 0.8% hyaluronic acid-using scanning electron microscopy. Tetracycline hydrochloride showed the greatest efficacy, exhibiting a significantly higher number of patent dentinal tubules compared to other agents. Thus, root surface conditioning enhances biocompatibility, promotes fibroblast adhesion and contributes to favourable periodontal healing and successful surgical outcomes.
牙根表面的机械预备会形成一层玷污层,这可能会阻碍结缔组织的重新附着。使用牙根处理剂来去除玷污层,暴露胶原纤维并促进组织再生的改善。因此,利用扫描电子显微镜评估五种牙根处理剂——20%柠檬酸、17%乙二胺四乙酸(EDTA)、37%磷酸、250mg/mL盐酸四环素和0.8%透明质酸的功效具有重要意义。盐酸四环素显示出最大的功效,与其他试剂相比,其开放的牙本质小管数量显著更多。因此,牙根表面处理可增强生物相容性,促进成纤维细胞黏附,并有助于实现良好的牙周愈合和成功的手术效果。