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内镜超声在肝硬化相关并发症管理中的应用——最新证据

Endoscopic ultrasound in the management of complications related to cirrhosis- recent evidence.

作者信息

Castleberry Drew T, Mann Rupinder, Tharian Benjamin, Thandassery Ragesh Babu

机构信息

Department of Internal Medicine, Division of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, AR 72202, United States.

Department of Internal Medicine, Division of Gastroenterology, Central Arkansas Veterans Healthcare System, Little Rock, AR 72202, United States.

出版信息

World J Gastrointest Endosc. 2025 Sep 16;17(9):108549. doi: 10.4253/wjge.v17.i9.108549.

DOI:10.4253/wjge.v17.i9.108549
PMID:40979066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12444283/
Abstract

Advanced endoscopic methods like endoscopic ultrasound (EUS) have recently been applied for the management of complications related to cirrhosis. This includes novel techniques to measure portal pressure gradients, esophageal, gastric, and ectopic varices management, and EUS-assisted treatment of liver tumors. Management of liver tumors has seen significant changes in recent years, and many minimally invasive procedures have been approved, especially in the management of liver cell carcinoma. These are specialized procedures and are performed only in patients with cirrhosis in specialized centers. There are concerns for complications in patients with cirrhosis due to their increased risk of bleeding and the altered hemostatic milieu. This minireview summarizes the recent evidence on using EUS in the management of cirrhosis-related complications.

摘要

像内镜超声(EUS)这样的先进内镜方法最近已被应用于肝硬化相关并发症的管理。这包括测量门静脉压力梯度的新技术、食管、胃和异位静脉曲张的管理以及EUS辅助治疗肝肿瘤。近年来,肝肿瘤的管理发生了显著变化,许多微创手术已获批准,尤其是在肝细胞癌的管理方面。这些都是专门的手术,仅在专业中心为肝硬化患者进行。由于肝硬化患者出血风险增加和止血环境改变,人们担心其会出现并发症。本综述总结了关于使用EUS管理肝硬化相关并发症的最新证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/021c636f9215/wjge-17-9-108549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/9beba75449a7/wjge-17-9-108549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/5b9176419715/wjge-17-9-108549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/021c636f9215/wjge-17-9-108549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/9beba75449a7/wjge-17-9-108549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/5b9176419715/wjge-17-9-108549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/258e/12444283/021c636f9215/wjge-17-9-108549-g003.jpg

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本文引用的文献

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JHEP Rep. 2025 May 29;7(8):101466. doi: 10.1016/j.jhepr.2025.101466. eCollection 2025 Aug.
2
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Correlates with Clinical Parameters and Liver Histology.内镜超声引导下的门体静脉压力梯度与临床参数及肝脏组织学相关。
Clin Gastroenterol Hepatol. 2025 Jan 30. doi: 10.1016/j.cgh.2024.12.022.
3
Safety and effectiveness of endoscopic ultrasound-guided gallbladder drainage in patients with cirrhosis: an international multicenter experience.
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Endoscopy. 2025 Jun;57(6):593-601. doi: 10.1055/a-2517-0927. Epub 2025 Jan 15.
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Reproducibility of EUS-guided shear wave elastography for assessment of hepatic fibrosis: a prospective pilot cohort study.超声内镜引导下剪切波弹性成像评估肝纤维化的可重复性:一项前瞻性试点队列研究。
Gastrointest Endosc. 2025 Mar;101(3):659-662. doi: 10.1016/j.gie.2024.10.064. Epub 2024 Nov 8.
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