Luo Jinxian, Yang Lei
Department of Thyroid and Mammary Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Courtyard No. 466 Xingang Middle Road, Haizhu District, 510310, Guangzhou, China.
Pingshan Hospital, Southern Medical University, Pingshan District Peoples' Hospital of Shenzhen, Pingshan Street, 518118, Shenzhou, Guangdong, P.R. China.
J Surg Case Rep. 2025 Sep 13;2025(9):rjaf733. doi: 10.1093/jscr/rjaf733. eCollection 2025 Sep.
Epithelioid sarcoma (ES) is a highly malignant soft tissue tumor characterized by its tendency to distant metastasis, regional lymph node involvement, and recurrence. ES frequently manifests as a deep dermal mass in the distal extremities of young adults. The variety of pathological morphology makes it clinically misdiagnosed as a granuloma or rheumatoid nodule frequently. In this case, we report a new case of a 56-year-old female who was diagnosed with metastatic ES on her left upper arm. The diagnosis was confirmed by pathological biopsy and immunohistochemistry analysis, and metastatic after surgical excision. Therefore, we should implement biopsy and immunohistochemistry methods on patients to rule out rare ES.
上皮样肉瘤（ES）是一种高度恶性的软组织肿瘤，其特征为易于发生远处转移、区域淋巴结受累及复发。ES常表现为年轻成人远端肢体的深部真皮肿物。其病理形态多样，临床上常被误诊为肉芽肿或类风湿结节。在此病例中，我们报告一例56岁女性，其左上臂被诊断为转移性ES。诊断经病理活检及免疫组化分析得以证实，且手术切除后出现转移。因此，我们应对患者实施活检及免疫组化方法以排除罕见的ES。
