Raveendran Arkiath Veettil
Department of Internal Medicine, Government Medical College, Kozhikode 673010, Kerala, India.
World J Diabetes. 2025 Sep 15;16(9):107517. doi: 10.4239/wjd.v16.i9.107517.
There is a paradigm shift in the approach to the treatment of type 2 diabetes mellitus (T2DM) based on recent research. "Twin cycle hypothesis" and remission of diabetes proved that diabetes is a disease due to excess fat accumulation above the personal fat threshold. Hence, weight reduction and, whenever possible, achievement of remission has become therapeutic target for the management of T2DM. Increasing evidence suggests that T2DM is a part of the spectrum of diseases caused by excess fat accumulation. Hence, it indeed is the need of the hour to update the terminologies to indicate that T2DM is part of the disease spectrum of excess fat accumulation to improve awareness among healthcare professionals and the public to achieve overall holistic management of the disease spectrum. In this short article, we analyze these factors and propose a new terminology for adaptation worldwide.
基于近期研究,2型糖尿病(T2DM)的治疗方法出现了范式转变。“双循环假说”和糖尿病缓解证明,糖尿病是一种由于个人脂肪阈值以上脂肪过度积累导致的疾病。因此,减轻体重并尽可能实现缓解已成为T2DM管理的治疗目标。越来越多的证据表明,T2DM是由脂肪过度积累引起的一系列疾病的一部分。因此,当下确实需要更新术语,以表明T2DM是脂肪过度积累疾病谱的一部分,从而提高医疗保健专业人员和公众的认识,以实现对该疾病谱的全面整体管理。在这篇短文中,我们分析了这些因素,并提出了一个供全球采用的新术语。