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将非酒精性脂肪性肝病重新定义为代谢相关脂肪性肝病:这合理吗?

Redefining non-alcoholic fatty liver disease to metabolic associated fatty liver disease: Is this plausible?

作者信息

Devi Jalpa, Raees Aimun, Butt Amna Subhan

机构信息

Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro 74800, Pakistan.

Department of Gastroenterology, Aga Khan University Hospital, Karachi 74800, Pakistan.

出版信息

World J Hepatol. 2022 Jan 27;14(1):158-167. doi: 10.4254/wjh.v14.i1.158.

DOI:10.4254/wjh.v14.i1.158
PMID:35126845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8790389/
Abstract

Recently, a single letter change has taken the world by storm. A group of experts have developed a consensus to upgrade the term non-alcoholic fatty liver disease (NAFLD) to metabolic associated fatty liver disease (MAFLD), suggesting that MAFLD would more accurately reflect not only the disease pathogenesis but would also help in patient stratification for management with NAFLD. However, the difference of opinion exists, which has made the NAFLD MAFLD debate the current talk of the town. This review will focus on the plausibility and implications of redefining NAFLD as MAFLD.

摘要

最近,一个字母的变化在全球引起了轰动。一组专家已达成共识,将非酒精性脂肪性肝病(NAFLD)这一术语升级为代谢相关脂肪性肝病(MAFLD),表明MAFLD不仅能更准确地反映疾病发病机制,还将有助于对NAFLD患者进行分层管理。然而,存在不同意见,这使得NAFLD与MAFLD的争论成为当前的热门话题。本综述将聚焦于将NAFLD重新定义为MAFLD的合理性及影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1927/8790389/3e41b4d534f9/WJH-14-158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1927/8790389/3e41b4d534f9/WJH-14-158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1927/8790389/3e41b4d534f9/WJH-14-158-g001.jpg

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Hepatol Forum. 2020 Sep 21;1(3):79-81. doi: 10.14744/hf.2020.2020.0024. eCollection 2020 Sep.
2
High incidence of hepatitis B core antibody positivity in metabolic-associated fatty liver disease-related cirrhosis.代谢相关脂肪性肝病相关肝硬化中乙肝核心抗体阳性的高发生率。
Hepatol Forum. 2021 Jan 8;2(1):20-25. doi: 10.14744/hf.2020.2020.0025. eCollection 2021 Jan.
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Biomedicines. 2025 Mar 28;13(4):812. doi: 10.3390/biomedicines13040812.
4
High Variability on Alcohol Intake Threshold in Articles Using the MAFLD Acronym.使用MAFLD首字母缩写的文章中酒精摄入阈值的高度变异性。
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Comparison of Outcomes Between Metabolic Dysfunction-Associated Fatty Liver Disease and Non-alcoholic Fatty Liver Disease: A Meta-Analysis.代谢功能障碍相关脂肪性肝病与非酒精性脂肪性肝病的结局比较:一项荟萃分析
Cureus. 2023 Aug 30;15(8):e44413. doi: 10.7759/cureus.44413. eCollection 2023 Aug.
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