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将非酒精性脂肪性肝病重新定义为代谢相关脂肪性肝病:这合理吗?

Redefining non-alcoholic fatty liver disease to metabolic associated fatty liver disease: Is this plausible?

作者信息

Devi Jalpa, Raees Aimun, Butt Amna Subhan

机构信息

Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro 74800, Pakistan.

Department of Gastroenterology, Aga Khan University Hospital, Karachi 74800, Pakistan.

出版信息

World J Hepatol. 2022 Jan 27;14(1):158-167. doi: 10.4254/wjh.v14.i1.158.

Abstract

Recently, a single letter change has taken the world by storm. A group of experts have developed a consensus to upgrade the term non-alcoholic fatty liver disease (NAFLD) to metabolic associated fatty liver disease (MAFLD), suggesting that MAFLD would more accurately reflect not only the disease pathogenesis but would also help in patient stratification for management with NAFLD. However, the difference of opinion exists, which has made the NAFLD MAFLD debate the current talk of the town. This review will focus on the plausibility and implications of redefining NAFLD as MAFLD.

摘要

最近,一个字母的变化在全球引起了轰动。一组专家已达成共识,将非酒精性脂肪性肝病(NAFLD)这一术语升级为代谢相关脂肪性肝病(MAFLD),表明MAFLD不仅能更准确地反映疾病发病机制,还将有助于对NAFLD患者进行分层管理。然而,存在不同意见,这使得NAFLD与MAFLD的争论成为当前的热门话题。本综述将聚焦于将NAFLD重新定义为MAFLD的合理性及影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1927/8790389/3e41b4d534f9/WJH-14-158-g001.jpg

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