"Emergence of a CTX-M-15-producing multidrug-resistance Haemophilus parainfluenzae in Southern Spain".
作者信息
Pérez-Vázquez María, Pérez-Carrasco Virginia, Aguilera-Franco María, Lara Noelia, Rivero-Rodríguez Mar, Navarro-Marí José María, Gutiérrez-Fernández José
机构信息
Laboratorio de Referencia e Investigación en Resistencia a Antibióticos e Infecciones Relacionadas con la Asistencia Sanitaria, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, 28222, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, 28029, Spain.
出版信息
Eur J Clin Microbiol Infect Dis. 2025 Sep 22. doi: 10.1007/s10096-025-05287-2.
Urogenital infections caused by Haemophilus parainfluenzae are becoming an emerging health problem. This, along with the increase in strains resistant to current antibiotic treatments, is making it difficult to control these infections. Therefore, it is important to monitor the emergence and spread of these strains, as well as their resistance to antibiotics. Our study describes a new urethral isolate of MDR with ESBLs from a hospital in southern Spain. Whole-genome sequencing has determined the production of extended-spectrum beta-lactamase (CTX-M), as well as the presence of other resistance genes. Furthermore, phylogenetic analysis with respect to other isolates has shown the presence of allelic differences between them, justifying the geographical spread of this clinical problem.
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