Castellano-Sánchez Leticia, Rosales-Castillo Antonio, Marcos-Rodríguez Raquel, Olvera-Porcel María Carmen, Navarro-Marí José María, Gutiérrez-Fernández José
Microbiology Laboratory, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria de Granada, 18012 Granada, Spain.
Clinical Medicine and Public Health Doctoral Program, PostGraduate School, University of Granada, 18012 Granada, Spain.
J Fungi (Basel). 2025 Jun 26;11(7):483. doi: 10.3390/jof11070483.
The presence of spp. in urine has traditionally been considered to be a colonization; however, in certain clinical circumstances, such as in critically ill patients, immunocompromised individuals, or those with chronic diseases, it gains greater relevance due to the possibility of active infection and complications. The aim of this study was to characterize the epidemiology (incidence, species distribution, demographic characteristics, and origin) of spp. isolates in urine through a retrospective cross-sectional analysis of urine culture isolates from clinical samples between January 2016 and December 2023. Out of a total of 111,656 urine cultures, spp. was isolated at 2.72% ( = 3037). The most frequently isolated species was (54.25%; 1646/3037), followed by (22.78%; 692/3037) and (10.2%; 311/3037). Advanced age (>70 years), male sex, presence of a urinary catheter, and origin from intensive care units, oncology, or surgical services were variables associated with a higher risk of candiduria, highlighting the relevance of candiduria in the presence of such clinical scenarios.
尿液中存在 spp. 传统上被认为是一种定植；然而，在某些临床情况下，如重症患者、免疫功能低下者或患有慢性疾病的患者中，由于存在活动性感染和并发症的可能性，其相关性更高。本研究的目的是通过对2016年1月至2023年12月临床样本的尿培养分离株进行回顾性横断面分析，来描述尿液中 spp. 分离株的流行病学特征（发病率、菌种分布、人口统计学特征和来源）。在总共111,656份尿培养中， spp. 的分离率为2.72%（n = 3037）。最常分离出的菌种是 （54.25%；1646/3037），其次是 （22.78%；692/3037）和 （10.2%；311/3037）。高龄（>70岁）、男性、存在导尿管以及来自重症监护病房、肿瘤科或外科科室是与念珠菌尿风险较高相关的变量，突出了在这些临床情况下念珠菌尿的相关性。
