Kiss Zoltán, Murányi Mihály, Nagy Attila, Flaskó Tibor
Department of Urology, University of Debrecen, Debrecen, Hungary.
Department of Health Informatics, Faculty of Health Sciences, University of Debrecen, Debrecen, Hungary.
PLoS One. 2025 Sep 23;20(9):e0331142. doi: 10.1371/journal.pone.0331142. eCollection 2025.
Anatomical endoscopic enucleation of the prostate (AEEP) has revolutionized the surgical treatment of benign prostatic hyperplasia, offering advantages over transurethral prostate resection (TURP). This study aimed to compare the effectiveness of the mushroom technique versus morcellation in en bloc transurethral bipolar prostate enucleation (TUEB) for prostates > 80 mL, hypothesizing that morcellation would reduce operative time.
We retrospectively reviewed 234 TUEB procedures performed between January 2018 and March 2024 at a tertiary university hospital. Patients were divided into two groups: the mushroom technique group (n = 116) and the morcellation group (n = 118). Demographic and clinical data were collected and outcomes, such as operative time, efficacy, and complications, were analyzed.
The median operative time was significantly longer in the mushroom cohort (80 [60-90] min) than in the morcellation cohort (60 [50-70] min) (p < 0.001). Efficacy, which was measured in g/min, was higher in the morcellation group (1.25 [1.01-1.44] g/min) than in the mushroom group (0.9 [0.76-1.03] g/min) (p < 0.001). Linear regression analysis showed that the prostate volume significantly influenced the operative time of the mushroom technique more than that of the morcellation technique. Complications were similar across the groups, with no need for blood transfusion or conversion to TURP.
Morcellation is an efficient method for tissue removal during bipolar prostate enucleation particularly for larger prostates, owing to its shorter operative time and consistent efficacy. Although the mushroom technique is a viable alternative, it is less efficient for larger glands. Nevertheless, both techniques demonstrated similar safety profiles and functional outcomes. Further multicenter trials are required to confirm these findings.
前列腺解剖性内镜剜除术(AEEP)彻底改变了良性前列腺增生的外科治疗方式,相较于经尿道前列腺切除术(TURP)具有诸多优势。本研究旨在比较蘑菇技术与粉碎术在经尿道双极前列腺剜除术(TUEB)中整块切除大于80 mL前列腺的有效性,假设粉碎术可缩短手术时间。
我们回顾性分析了2018年1月至2024年3月在一家三级大学医院进行的234例TUEB手术。患者分为两组:蘑菇技术组(n = 116)和粉碎术组(n = 118)。收集人口统计学和临床数据,并分析手术时间、疗效和并发症等结果。
蘑菇技术组的中位手术时间(80 [60 - 90]分钟)显著长于粉碎术组(60 [50 - 70]分钟)(p < 0.001)。以克/分钟衡量的疗效,粉碎术组(1.25 [1.01 - 1.44]克/分钟)高于蘑菇技术组(0.9 [0.76 - 1.03]克/分钟)(p < 0.001)。线性回归分析表明,前列腺体积对蘑菇技术手术时间的影响显著大于对粉碎术技术的影响。两组并发症相似,均无需输血或转为TURP。
粉碎术是双极前列腺剜除术中一种有效的组织切除方法,特别是对于较大的前列腺,因其手术时间短且疗效稳定。尽管蘑菇技术是一种可行的替代方法,但对于较大腺体效率较低。然而,两种技术的安全性和功能结局相似。需要进一步的多中心试验来证实这些发现。