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资源有限环境下的出生窒息:尼泊尔新生儿护理面临的挑战及影响

Birth asphyxia in a resource-limited setting: Challenges and implications for neonatal care in Nepal.

作者信息

Adhikari Keshav, Khan Sajjad Ahmed, Yadav Birendra Kumar, Bhattarai Chaitanya Darshan, Basnet Kumar, Bajgain Arun, Budhathoki Anu, Aryal Ananda, Thapa Jyoti

机构信息

Department of Pediatrics, Nepal Medical College Teaching Hospital.

Birat Medical College Teaching Hospital, Morang, Nepal.

出版信息

Medicine (Baltimore). 2025 Sep 19;104(38):e44537. doi: 10.1097/MD.0000000000044537.

Abstract

Birth asphyxia is a common problem especially in low resource developing countries like Nepal during the delivery. Birth asphyxia remains a major cause of mortality and morbidity worldwide and specially in developing countries like Nepal. Despite the advancement in medical science birth asphyxia still remains a major problem in newborn and preventing the risk factors after evaluating remains the center of reducing the prevalence. Proper healthcare protocols, early intervention and appropriate management is important for preventing long term sequalae and mortality. This study aims to assess the prevalence and risk factors of birth asphyxia in our institution. This hospital- based cross sectional descriptive study aimed to study the corelation between perinatal asphyxia with obstetrics and neonatal risk factors and to identify the complications of perinatal asphyxia. A total of 56 neonates were enrolled, and the data were analyzed using Statistical Package for the Social Sciences (SPSS, Chicago) version 21. Prevalence of birth asphyxia in our setting is 2.1%. A significant relationship was found between meconium stained liqor and birth asphyxia. Mortality occurred in 7% of the neonates. As in our part of the world where the studies are very limited this study will be a great asset to evaluate the incidence and determine the preventable risk factors of birth asphyxia thus helping in reducing the grave sequalae associated with birth asphyxia.

摘要

出生窒息是一个常见问题,尤其是在尼泊尔这样资源匮乏的发展中国家分娩期间。出生窒息仍然是全球尤其是像尼泊尔这样的发展中国家死亡和发病的主要原因。尽管医学取得了进步,但出生窒息在新生儿中仍然是一个主要问题,评估后预防危险因素仍然是降低其患病率的核心。适当的医疗保健方案、早期干预和恰当管理对于预防长期后遗症和死亡至关重要。本研究旨在评估我们机构中出生窒息的患病率和危险因素。这项基于医院的横断面描述性研究旨在研究围产期窒息与产科和新生儿危险因素之间的相关性,并确定围产期窒息的并发症。共纳入56例新生儿,并使用社会科学统计软件包(SPSS,芝加哥)第21版对数据进行分析。我们研究环境中出生窒息的患病率为2.1%。发现羊水胎粪污染与出生窒息之间存在显著关系。7%的新生儿发生了死亡。由于在我们这个地区相关研究非常有限,本研究将成为评估出生窒息发病率和确定可预防危险因素的重要资源,从而有助于减少与出生窒息相关的严重后遗症。

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