Liang Shicong, Huang Lei, Tang Shu-Tong, Li Hong-Xing, Huang Jia-Wei, Zhou Wen-Qing, Xia Zhi-Chun
The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.
Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China.
Front Psychiatry. 2025 Sep 8;16:1652534. doi: 10.3389/fpsyt.2025.1652534. eCollection 2025.
This study aimed to explore the current acceptance of advance care planning (ACP) among patients with schizophrenia and investigate the influencing factors.
A cross-sectional study was conducted from September 2023 to January 2024 using a convenience sampling method. A total of 225 patients with schizophrenia were selected from a Grade A, Class III Psychiatric Hospital and the Department of Psychiatry of a Grade A, Class III General Hospital in Guangzhou, China. The Advance Care Planning Readiness Scale, the Chinese version of the Brief Neurocognitive Test Battery(C-BCT), the Brief Psychiatric Rating Scale(BPRS), and the Medication Adherence Questionnaire(MAQ) were used to survey the patients with schizophrenia.
Mean ACP readiness score was 84.76 ± 11.97, with 55.6% showing high acceptance. Readiness positively correlated with age (r=0.161, p=0.021) and hospitalization frequency (r=0.235, p=0.001), and negatively with symptom severity (r=-0.159, p=0.022). Patients with comorbidities (p=0.001) or personal/family health crises (p=0.033) had higher readiness. Regression analysis identified cognitive impairment, religious beliefs, hospitalization frequency, and medication adherence as key predictors (R²=0.118, p<0.001), explaining 11.8% of variance.
Schizophrenia patients demonstrate higher than average ACP acceptance, with 55.6% of the patients showing a high level of acceptance. Improved medication adherence, frequent hospitalizations, religious beliefs and reduced thinking disorder severity. Culturally sensitive health education is recommended to facilitate ACP discussions in clinical practice.
本研究旨在探讨精神分裂症患者对预先护理计划(ACP)的当前接受情况,并调查影响因素。
采用便利抽样法,于2023年9月至2024年1月进行横断面研究。从中国广州的一家三甲精神病专科医院和一家三甲综合医院的精神科选取了225例精神分裂症患者。使用预先护理计划准备度量表、中文版简易神经认知测试电池(C-BCT)、简明精神病评定量表(BPRS)和药物依从性问卷(MAQ)对精神分裂症患者进行调查。
ACP准备度平均得分为84.76±11.97,55.6%的患者表现出高度接受。准备度与年龄(r=0.161,p=0.021)和住院频率(r=0.235,p=0.001)呈正相关,与症状严重程度呈负相关(r=-0.159,p=0.022)。患有合并症(p=0.001)或个人/家庭健康危机(p=0.033)的患者准备度更高。回归分析确定认知障碍、宗教信仰、住院频率和药物依从性为关键预测因素(R²=0.118,p<0.001),解释了11.8%的方差。
精神分裂症患者对ACP的接受程度高于平均水平,55.6%的患者表现出高度接受。改善药物依从性、频繁住院、宗教信仰和减轻思维障碍严重程度。建议开展具有文化敏感性的健康教育,以促进临床实践中的ACP讨论。