McGreal Noah Kevin, Winnegrad Zachary Dylan, Diorio Gregory Joseph, Gefen Ron, Birbe Ruth Carolina, Arriola Aileen Grace P
Cooper Medical School of Rowan University, Camden, New Jersey, USA.
Urology Division, Department of Surgery, Cooper University Health Care, Camden, New Jersey, USA.
Case Rep Urol. 2025 Sep 15;2025:8149819. doi: 10.1155/criu/8149819. eCollection 2025.
Juxtaglomerular cell tumors (JCTs), also known as reninomas, are rare masses with an extremely low risk of malignancy, but their endocrine activity can lead to medication-resistant hypertension and electrolyte imbalances, which may harm patients. Approximately 150 cases have been documented in the literature. In this report, we describe the case of a 40-year-old male with a complex cystic renal mass, prior hemorrhagic strokes, and hypertension who underwent surgical resection. The final pathology confirmed a JCT, marking the first case on record diagnosed at our institution in 20 years. Following surgery, the patient's hypertension improved, and his need for medication decreased. We suggest that physicians managing renal masses that are otherwise suitable for surveillance should include JCT in their differential diagnosis and consider surgical removal if hypertension is present.
肾球旁细胞瘤（JCTs），也称为肾素瘤，是罕见的肿块，恶性风险极低，但其内分泌活性可导致药物抵抗性高血压和电解质失衡，这可能对患者造成伤害。文献中已记录了约150例病例。在本报告中，我们描述了一名40岁男性的病例，该患者有复杂的囊性肾肿块、既往出血性中风病史和高血压，接受了手术切除。最终病理证实为肾球旁细胞瘤，这是我们机构20年来记录在案的首例确诊病例。手术后，患者的高血压得到改善，药物需求减少。我们建议，对于管理那些原本适合监测的肾肿块的医生，应将肾球旁细胞瘤纳入鉴别诊断，如果存在高血压，应考虑手术切除。
