Clarke Karen, Naidu Sathyabama, Malik Albahi, Berkowitz David, Hampton Stephanie, Hall Mary Ann Kirkconnell, Sueblinvong Viranuj
Division of Hospital Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
J Investig Med High Impact Case Rep. 2025 Jan-Dec;13:23247096251381142. doi: 10.1177/23247096251381142. Epub 2025 Sep 24.
Plastic bronchitis is a rare pulmonary condition, most frequently observed in children, that can lead to respiratory failure due to airway obstruction. We present the case of a 50-year-old man with occupational exposure to drywall who experienced recurrent episodes of hypoxic respiratory failure, necessitating multiple intubations. He was initially diagnosed with interstitial lung disease and treated with corticosteroids, but showed minimal clinical improvement. Subsequent flexible bronchoscopy revealed a bronchial cast obstructing the left mainstem bronchus. As plastic bronchitis is typically associated with disorders that cause abnormal lymphatic drainage, thoracic duct embolization was performed. The patient also underwent cryoprobe-assisted bronchoscopy for cast removal. Performance of these 2 procedures led to improved oxygenation and resolution of hypoxic respiratory failure, with no further need for mechanical ventilation.