Han Shuo, Wang Guang-Ming, Dai Da-Wei, Zhang Dan-Feng
Department of Neurosurgery, Shanghai Changzheng Hospital, Shanghai, 200003, China.
Department of Neurosurgery, Shanghai Renji Hospital, Shanghai, 200127, China.
Int J Surg Case Rep. 2025 Sep 21;136:111966. doi: 10.1016/j.ijscr.2025.111966.
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are benign and slowly growing fibro-osseous lesions of the nervous system.
We report two rare cases of spinal CAPNON and provide a literature review.
A 33-year-old woman with back pain underwent lumbar magnetic resonance imaging (MRI), revealing a large intradural mass (1.5 × 0.9 × 10.6cm) at L2-S1. Postoperative MRI scan performed 3 years after surgery confirmed no recurrence. A 64-year-old woman with lower limb numbness and gait instability underwent lumbar MRI, revealing an L3 intradural mass (1.1 × 0.3 × 1.6cm). Lower limb numbness were resolved after surgery during 1 year follow-up.
Accurate recognition of CAPNON is essential to guide appropriate surgical intervention due to its favorable prognosis. In these situations, complete resection and radiological follow-up are highly recommended.
神经轴钙化性假瘤（CAPNON）是神经系统的良性、生长缓慢的纤维骨性病变。
我们报告两例罕见的脊柱CAPNON病例并进行文献复习。
一名33岁背痛女性接受腰椎磁共振成像（MRI）检查，显示L2-S1水平有一个巨大的硬膜内肿块（1.5×0.9×10.6cm）。术后3年的MRI扫描证实无复发。一名64岁下肢麻木和步态不稳的女性接受腰椎MRI检查，显示L3水平硬膜内肿块（1.1×0.3×1.6cm）。术后1年随访期间下肢麻木症状消失。
由于CAPNON预后良好，准确识别对于指导适当的手术干预至关重要。在这些情况下，强烈建议完整切除并进行影像学随访。
