Simmons D A
Immunology. 1971 Jan;20(1):17-24.
Complement fixation inhibition studies with oligosaccharides of known molecular structure have shown that the epitopes of O-antigens I, II, III, IV, V and 7,8 are disaccharide sequences of α-D-glucosyl-(1→4)--acetyl-D-glucosamine, α-D-glucosyl-(1→4)-L-rhamnose, 2--acetyl-α-D-glucosyl-(1→2)-L-rhamnose, α-D-glucosyl-(1→6)--acetyl-D-glucosamine, α-D-glucosyl-(1→3)-L-rhamnose and α-D-glucosyl-(1→2)-L-rhamnose respectively. The paratope of rabbit antibody appears to have molecular dimensions corresponding to at least two, but not more than three, sugar residues.
对已知分子结构的寡糖进行的补体固定抑制研究表明，O抗原I、II、III、IV、V和7,8的表位分别是α-D-葡糖基-（1→4）-N-乙酰-D-葡糖胺、α-D-葡糖基-（1→4）-L-鼠李糖、2-N-乙酰-α-D-葡糖基-（1→2）-L-鼠李糖、α-D-葡糖基-（1→6）-N-乙酰-D-葡糖胺、α-D-葡糖基-（1→3）-L-鼠李糖和α-D-葡糖基-（1→2）-L-鼠李糖的二糖序列。兔抗体的互补位似乎具有对应于至少两个但不超过三个糖残基的分子尺寸。
