Wang Wenxuan, Lu Haiying, Yan Chuchu, Shan Yawei
School of Nursing, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Front Med (Lausanne). 2025 Sep 9;12:1665680. doi: 10.3389/fmed.2025.1665680. eCollection 2025.
Home-based traditional Chinese exercise (TCE) has been proven to be a promising method for improving knee function in patients with knee osteoarthritis (KOA). However, no consensus has been reached among studies on its effectiveness. The study aims to evaluate the effectiveness and safety of the home-based TCE, including Tai Chi, Baduanjin, Yijinjing, and Wuqinxi, for improving knee function, pain, quality of life, and mental health in patients with KOA.
Eight electronic databases including PubMed, The Cochrane Library, EMBASE, Web of Science, CNKI, Wanfang, VIP, and SinoMed were systematically searched for randomized controlled trials (RCTs) from their inception to February 2025. Two reviewers independently extracted data and assessed methodological quality using the Cochrane Risk of Bias tool. The meta-analysis was conducted using Review Manager 5.4.
Eleven RCTs involving 854 participants were included. TCE showed a significant improvement in general knee function (SMD = -0.61; 95% CI: -1.02 to -0.20; = 0.003), pain (SMD = -0.52; 95% CI: -0.88 to -0.15; = 0.006), the physical quality of life (SMD = -0.41; 95% CI: -0.80 to -0.02; = 0.04), and depression (SMD = -1.00; 95% CI: -1.74 to -0.26; = 0.008) with minimal adverse events. However, data on stiffness and cost-effectiveness were limited.
Home-based TCE is a safe and effective complementary intervention for managing KOA, particularly when integrated into a structured programme combining supervised sessions and home-based practice. Further high-quality RCTs with standardized protocols and longer follow-up are warranted.
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024503800, Identifier CRD42024503800.
家庭式传统中医运动（TCE）已被证明是改善膝关节骨关节炎（KOA）患者膝关节功能的一种有前景的方法。然而，关于其有效性的研究尚未达成共识。本研究旨在评估家庭式TCE（包括太极拳、八段锦、易筋经和五禽戏）对改善KOA患者膝关节功能、疼痛、生活质量和心理健康的有效性及安全性。
系统检索包括PubMed、Cochrane图书馆、EMBASE、科学网、中国知网、万方、维普和中国生物医学文献数据库在内的8个电子数据库，检索自数据库建库至2025年2月的随机对照试验（RCT）。两名评价员独立提取数据，并使用Cochrane偏倚风险工具评估方法学质量。使用Review Manager 5.4进行荟萃分析。
纳入11项RCT，共854名参与者。TCE在总体膝关节功能（标准化均数差[SMD]= -0.61；95%置信区间[CI]：-1.02至-0.20；P = 0.003）、疼痛（SMD = -0.52；95% CI：-0.88至-0.15；P = 0.006）、身体生活质量（SMD = -0.41；95% CI：-0.80至-0.02；P = 0.04）和抑郁（SMD = -1.00；95% CI：-1.74至-0.26；P = 0.008）方面有显著改善，不良事件极少。然而，关于僵硬和成本效益的数据有限。
家庭式TCE是管理KOA的一种安全有效的辅助干预措施，特别是当它被纳入一个结合了监督课程和家庭练习的结构化方案时。有必要开展进一步的高质量RCT，采用标准化方案并进行更长时间的随访。
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024503800，标识符CRD42024503800。
