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一名儿科患者的牙源性纤维黏液瘤:一种罕见的侵袭性肿瘤,具有复发性和致命性结局。

Odontogenic Fibromyxoma in a Pediatric Patient: A Rare Aggressive Neoplasm With Recurrent and Fatal Outcome.

作者信息

Abdullah Mohd Faizal, Fauzi Fattirah Auni

机构信息

Oral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus, Kota Bharu, Kelantan, Malaysia.

Oral and Maxillofacial Surgery Unit, Hospital Universiti Sains Malaysia, Health Campus, Kota Bharu, Kelantan, Malaysia.

出版信息

Case Rep Dent. 2025 Sep 16;2025:2439166. doi: 10.1155/crid/2439166. eCollection 2025.

Abstract

Odontogenic myxomas, a rare intraosseous neoplasm, usually present as a slow rate of bony expansion and are painless in nature, and eventually lead to facial deformity. The tumor is thought to arise from the mesenchyme of the tooth germ and is associated with an impacted tooth. The fact that this tumor is widely distributed throughout the jaws and facial bones suggests its odontogenic neoplasm origin. Furthermore, its histology is similar to that of the developing tooth's stellate reticulum. Fibromyxomas account for a small proportion of all myxomas. We herein report a complex case of recurrent odontogenic fibromyxoma that requires multiple surgical interventions and recurrences that lead to the death of the patient due to disease progression.

摘要

牙源性黏液瘤是一种罕见的骨内肿瘤,通常表现为缓慢的骨质膨胀,本质上无痛,最终导致面部畸形。该肿瘤被认为起源于牙胚的间充质,与阻生牙有关。这种肿瘤广泛分布于颌骨和面部骨骼,这表明其起源于牙源性肿瘤。此外,其组织学与发育中牙齿的星网状层相似。纤维黏液瘤在所有黏液瘤中占比很小。我们在此报告一例复发性牙源性纤维黏液瘤的复杂病例,该病例需要多次手术干预,且因疾病进展导致复发,最终患者死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/12457052/f1e01e925ce8/CRID2025-2439166.001.jpg

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