Alhousami Thabet, Sabharwal Amarpreet, Gupta Shivane, Aguirre Alfredo, Park Etern, Kramer Jill M
Department of Oral Diagnostics Sciences, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Department of Basic and Clinical Oral Sciences, Faculty of Dentistry, Umm Al-Qura University, Makkah, Saudi Arabia.
Head Neck Pathol. 2018 Mar;12(1):44-51. doi: 10.1007/s12105-017-0823-0. Epub 2017 May 16.
We report a case of fibromyxoma of the mandible, a rare benign odontogenic tumor. Our patient presented in the first trimester of pregnancy with a large mass in the right body of the mandible exhibiting displacement of teeth and destruction of an extensive area of the mandibular bone. The mass was biopsied and diagnosed as a fibromyxoma. The large size of the tumor dictated a wide mandibular resection. We will review the clinical, radiographic, and histologic features of fibromyxoma and discuss its differential diagnoses. In addition, we will provide an overview of patient management. Fibromxyoma is a benign gnathic tumor that can be locally aggressive. To ensure appropriate treatment, it is important to distinguish this neoplasm from other mimickers in which myxoid, spindle mesenchymal cell proliferation is prominent.
我们报告一例下颌骨纤维黏液瘤,这是一种罕见的良性牙源性肿瘤。我们的患者在妊娠早期就诊,下颌骨右侧体部有一个大肿块,导致牙齿移位并破坏了下颌骨的大片区域。对该肿块进行活检,诊断为纤维黏液瘤。肿瘤体积较大,需要进行广泛的下颌骨切除术。我们将回顾纤维黏液瘤的临床、影像学和组织学特征,并讨论其鉴别诊断。此外,我们将概述患者的治疗管理。纤维黏液瘤是一种良性颌骨肿瘤,可具有局部侵袭性。为确保得到恰当治疗,将这种肿瘤与其他以黏液样、梭形间充质细胞增殖显著的相似肿瘤区分开来很重要。