Vignesh Shanmugam, Ahmad Khursheed, Oh Tae Hwan
School of Chemical Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Republic of Korea.
Biosensors (Basel). 2025 Aug 25;15(9):560. doi: 10.3390/bios15090560.
Nickel-based metal-organic frameworks (Ni-MOFs) have received enormous amounts of attention from the scientific community due to their excellent porosity, larger specific surface area, tunable structure, and intrinsic redox properties. In previous years, Ni-MOFs and their hybrid composite materials have been extensively explored for electrochemical sensing applications. As per the reported literature, Ni-MOF-based hybrid materials have been used in the fabrication of electrochemical sensors for the monitoring of ascorbic acid, glucose, L-tryptophan, bisphenol A, carbendazim, catechol, hydroquinone, 4-chlorophenol, uric acid, kaempferol, adenine, -cysteine, etc. The presence of synergistic effects in Ni-MOF-based hybrid materials plays a crucial role in the development of highly selective electrochemical sensors. Thus, Ni-MOF-based materials exhibited enhanced sensitivity and selectivity with reasonable real sample recovery, which suggested their potential for practical applications. In addition, Ni-MOF-based hybrid composites were also adopted as electrode modifiers for the development of supercapacitors. The Ni-MOF-based materials demonstrated excellent specific capacitance at low current densities with reasonable cyclic stability. This review article provides an overview of recent advancements in the utilization of Ni-MOF-based electrode modifiers with metal oxides, carbon-based materials, MXenes, polymers, and LDH, etc., for the electrochemical detection of environmental pollutants and biomolecules and for supercapacitor applications. In addition, Ni-based bimetallic and trimetallic catalysts and their composites have been reviewed for electrochemical sensing and supercapacitor applications. The key challenges, limitations, and future perspectives of Ni-MOF-based materials are discussed. We believe that the present review article may be beneficial for the scientific community working on the development of Ni-MOF-based materials for electrochemical sensing and supercapacitor applications.
镍基金属有机框架材料（Ni-MOFs）因其优异的孔隙率、较大的比表面积、可调控的结构以及固有的氧化还原特性，受到了科学界的广泛关注。在过去几年中，Ni-MOFs及其杂化复合材料已被广泛用于电化学传感应用的探索。根据已发表的文献，基于Ni-MOFs的杂化材料已被用于制造电化学传感器，用于监测抗坏血酸、葡萄糖、L-色氨酸、双酚A、多菌灵、邻苯二酚、对苯二酚、4-氯苯酚、尿酸、山奈酚、腺嘌呤、半胱氨酸等。基于Ni-MOFs的杂化材料中协同效应的存在在高选择性电化学传感器的开发中起着至关重要的作用。因此，基于Ni-MOFs的材料表现出增强的灵敏度和选择性，同时具有合理的实际样品回收率，这表明它们具有实际应用潜力。此外，基于Ni-MOFs的杂化复合材料也被用作电极修饰剂来开发超级电容器。基于Ni-MOFs的材料在低电流密度下表现出优异的比电容，同时具有合理的循环稳定性。这篇综述文章概述了近年来基于Ni-MOFs的电极修饰剂与金属氧化物、碳基材料、MXenes、聚合物和层状双氢氧化物等在环境污染物和生物分子的电化学检测以及超级电容器应用方面的最新进展。此外，还综述了镍基双金属和三金属催化剂及其复合材料在电化学传感和超级电容器应用方面的情况。讨论了基于Ni-MOFs材料的关键挑战、局限性和未来展望。我们相信，这篇综述文章可能对致力于开发用于电化学传感和超级电容器应用的基于Ni-MOFs材料的科学界有益。
