Gao Pan, Hussain Mian Zahid, Gryc David, Mukherjee Soumya, Zhou Zhenyu, Li Weijin, Jentys Andreas, Elsner Martin, Fischer Roland A
Inorganic and Metal-Organic Chemistry, Department of Chemistry, School of Natural Sciences and Catalysis Research Center, Technical University of Munich (TUM), Lichtenbergstraße 4, 85748, Garching, Germany.
Inorganic and Metal-Organic Chemistry, Department of Chemistry, School of Natural Sciences and Catalysis Research Center, Technical University of Munich (TUM), Lichtenbergstraße 4, 85748, Garching, Germany.
Biosens Bioelectron. 2025 Oct 15;286:117598. doi: 10.1016/j.bios.2025.117598. Epub 2025 May 19.
Electrochemical (EC) sensing of bisphenol A (BPA), a notorious persistent contaminant, is of pressing interest. However, the state-of-the-art BPA sensors are challenged by two performance parameters: limited EC catalysis and sensitivity. Herein, a two-dimensional (2D) metal-organic framework (MOF) superstructure-derived NiP@C probe elicits a novel EC sensor that exhibits high-efficiency BPA detection. Thanks to the abundant Ni active sites exposed uniformly on cross-linked layers stemming from the inherited 2D-MOF superstructures as the precursors, high conductivity results from the organic linkers-derived graphitic carbon. The prepared NiP@C composites-based EC sensors demonstrated exceptional BPA-induced sensing responses with a wide dynamic response range, high sensitivity of 0.951 μA cm·μM, a low limit of detection (LOD, 56.8 nM) in the linear range of 1 μM-100 μM. Below 1 μM, the response followed the logarithm of BPA concentrations, indicating the potential for detection down to 5 pM. The excellent selectivity in the presence of similar interferents, combined with high reproducibility and chemical stability, underscores the potential of 2D MOF-derived NiP@C for accurate monitoring of hazardous phenols, opening new avenues for environmental sensing and remediation.
