Guo Anjie, Zhang Yuan, Jiang Meifeng, Chen Li, Jiang Xinrong, Zou Xiaobo, Sun Zongbao
Department of Food & Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
The Quality Monitoring Center for Food and Strategic Reserves of Zhenjiang City, Zhenjiang 212001, China.
Biosensors (Basel). 2025 Sep 21;15(9):629. doi: 10.3390/bios15090629.
The presence of hazardous substances in food poses a serious threat to our health. It is important to develop fast, convenient, and inexpensive assays for on-site sensitive analysis of various hazards in food. With the emergence and popularization of aptamers and biosensors, aptasensors have gradually become one of the most important detection techniques for substances such as nucleic acids and small molecules. This paper reviews the recent research progress in the field of aptasensor based on different technologies (such as electrochemistry, fluorescence, colorimetry, among others) for the rapid detection of hazards (such as foodborne pathogens, mycotoxins, pesticides, among others) in food. In addition, the current challenges of different aptasensors are described for the readers, and the future direction of aptasensors is envisioned by comparing the different technologies in order to develop a more suitable aptasensor. This review will not only promote the advancement of aptasensors but also their practical application in daily life to safeguard human health and food safety.
食品中有害物质的存在对我们的健康构成严重威胁。开发快速、便捷且廉价的检测方法用于食品中各种危害的现场灵敏分析非常重要。随着适配体和生物传感器的出现与普及，适配体传感器已逐渐成为用于检测核酸和小分子等物质的最重要检测技术之一。本文综述了基于不同技术（如电化学、荧光、比色法等）的适配体传感器在快速检测食品中危害（如食源性病原体、霉菌毒素、农药等）领域的最新研究进展。此外，还向读者介绍了不同适配体传感器当前面临的挑战，并通过比较不同技术对适配体传感器的未来发展方向进行了展望，以期开发出更合适的适配体传感器。这篇综述不仅将推动适配体传感器的发展，还将促进其在日常生活中的实际应用，以保障人类健康和食品安全。
