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免疫功能正常的成年人中表现为过敏性鼻炎的鼻蝇蛆病:14例成人病例系列

Nasal Myiasis Mimicking Allergic Rhinitis in Immunocompetent Adults: Case Series of 14 Adults.

作者信息

Mezri Sameh, Ammar Mohamed Anas, Mtibaa Latifa, Mnasria Sleheddine, Halwani Chiraz, Akkari Khemaies

机构信息

ENT Department, Military Hospital of Tunis, Tunis 1008, Tunisia.

Faculty of Medicine of Tunis, University of Tunis El-Manar, Tunis 1068, Tunisia.

出版信息

Trop Med Infect Dis. 2025 Sep 9;10(9):257. doi: 10.3390/tropicalmed10090257.

Abstract

BACKGROUND

Human nasal myiasis is a rare zoonotic infection caused by with a non-specific clinical presentation that can mimic more common conditions such as allergic rhinitis.

OBJECTIVE

To report a series of nasal myiasis cases in immunocompetent individuals, emphasizing the clinical presentation and complementary investigations (endoscopic findings, parasitological identification, skin prick tests, and imaging studies) that facilitate differential diagnosis from allergic rhinitis and enable early treatment.

METHODS

We conducted a retrospective study including cases of nasal myasis diagnosed and managed at the ENT department of the Military Hospital of Tunis over an 18-year period (2007-2025). Demographic, clinical, diagnostic, and therapeutic data were analyzed.

RESULTS

The mean age was 43 years, with a female predominance. Most patients presented with acute rhinological symptoms initially suggestive of allergic rhinitis. Nasal endoscopy revealed larvae in 79% of cases with parasitological confirmation of . Facial CT scans performed in five cases (36%) were unremarkable. Management consisted of multiple daily nasal saline irrigations and albendazole, in association with oral corticosteroids and antihistamines, resulting in symptom resolution within an average of 4 days.

CONCLUSIONS

Nasal myiasis should be considered in atypical or treatment-resistant rhinitis. Nasal endoscopy is essential for diagnosis.

摘要

背景

人体鼻蝇蛆病是一种由[未提及具体病因]引起的罕见人畜共患感染,临床表现不具有特异性,可类似过敏性鼻炎等更常见疾病。

目的

报告一系列免疫功能正常个体的鼻蝇蛆病病例,强调有助于与过敏性鼻炎进行鉴别诊断并实现早期治疗的临床表现及辅助检查(内镜检查结果、寄生虫鉴定、皮肤点刺试验和影像学检查)。

方法

我们进行了一项回顾性研究,纳入了突尼斯军事医院耳鼻喉科在18年期间(2007 - 2025年)诊断和治疗的鼻蝇蛆病病例。对人口统计学、临床、诊断和治疗数据进行了分析。

结果

平均年龄为43岁,女性居多。大多数患者最初表现为急性鼻科症状,最初提示为过敏性鼻炎。79%的病例经鼻内镜检查发现幼虫,并经寄生虫学证实。5例(36%)患者进行的面部CT扫描无异常。治疗包括每日多次鼻腔生理盐水冲洗和阿苯达唑,并联合口服糖皮质激素和抗组胺药,平均4天内症状缓解。

结论

对于非典型或难治性鼻炎应考虑鼻蝇蛆病。鼻内镜检查对诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/137b/12474202/9efbebe921a6/tropicalmed-10-00257-g001.jpg

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