Bennati Elena, Pozza Alice, Ciofi Daniele, Mantini Sara, Spaziani Gaia, Tomberli Alessia, Angileri Salvatore, Olivotto Iacopo, Favilli Silvia
Cardiology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Paediatric Cardiology Unit, Department of Women's and Children's Health, University of Padua, 35122 Padova, Italy.
Children (Basel). 2025 Sep 2;12(9):1171. doi: 10.3390/children12091171.
Survival rates for childhood cancer patients (CCSs) have increased due to new treatments. Cardiovascular disease (CVD) is the leading cause of non-cancer morbidity and mortality in CCSs. CVD is the result of direct cardiovascular (CV) damage caused by cancer treatment and accelerated atherosclerosis. CCSs are at increased risk of metabolic syndrome, yet CV risk factors are underdiagnosed and undertreated in this population. A structured transition care plan plays a key role in promoting greater awareness of the importance of appropriate CV risk management and a healthy lifestyle. This narrative review aims to provide a comprehensive illustration of how transition programs face many barriers in daily practice and the need for a widespread transition culture.
由于新的治疗方法，儿童癌症患者（CCSs）的生存率有所提高。心血管疾病（CVD）是CCSs中非癌症发病和死亡的主要原因。CVD是癌症治疗引起的直接心血管（CV）损伤和动脉粥样硬化加速的结果。CCSs患代谢综合征的风险增加，然而该人群中的CV危险因素未得到充分诊断和治疗。结构化的过渡护理计划在提高对适当CV风险管理和健康生活方式重要性的认识方面起着关键作用。本叙述性综述旨在全面说明过渡项目在日常实践中面临许多障碍以及广泛建立过渡文化的必要性。
