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自闭症性足尖行走:干预措施的叙述性综述及与特发性足尖行走的比较

The Autistic Toe Walking: A Narrative Review for Interventions and Comparison with Idiopathic Toe Walking.

作者信息

de Angeli Luiz Renato Agrizzi, Serafim Bárbara Lívia Corrêa, Masquijo Julio Javier

机构信息

Department of Orthopedics and Traumatology, Hospital Israelita Albert Einstein, São Paulo 05652-900, SP, Brazil.

Department of Orthopedics and Traumatology, University of São Paulo, São Paulo 05402-000, SP, Brazil.

出版信息

Children (Basel). 2025 Sep 8;12(9):1198. doi: 10.3390/children12091198.

Abstract

BACKGROUND/OBJECTIVES: Idiopathic toe walking (ITW) is a diagnosis of exclusion in children who demonstrate a persistent toe-walking gait without an identifiable underlying neuromuscular or orthopedic pathology. The classification of toe-walking behavior (TWB) in children with Autism Spectrum Disorder (ASD) remains an area of debate, with some considering it a part of the broader ITW spectrum, while others view it as a distinct entity. Children with TWB associated with ASD (Autistic Toe Walking-ATW) present unique clinical challenges. This subgroup exhibits a higher prevalence of toe walking, and their gait patterns are often associated with underlying neurodevelopmental differences, frequently leading to increased resistance to conventional treatment approaches and higher rates of persistence and recurrence. This narrative review aims to summarize the available evidence on interventions for ATW, highlight differences compared to ITW and discuss implications for clinical practice.

METHODS

A literature search was performed, including articles that addressed interventions for toe walking in children with ASD.

RESULTS

The literature is limited and heterogeneous. Identified interventions include physiotherapy, orthoses, botulinum toxin injections, serial casting, and surgical procedures. Evidence of effectiveness is scarce, with most studies consisting of small case series. ATW differs from classic ITW in some aspects of pathophysiology and clinical presentation. Treatment decisions should balance potential benefits with risks, particularly regarding repeated anesthesia exposure during casting versus earlier surgical options.

CONCLUSIONS

Evidence for managing ATW is limited. While comparisons to ITW may be useful, clinicians must recognize that they present distinct characteristics. Future research should focus on standardized definitions and controlled trials to guide management.

摘要

背景/目的:特发性足尖行走(ITW)是对那些表现出持续足尖行走步态且无明确潜在神经肌肉或骨科病理状况的儿童所做出的排除性诊断。自闭症谱系障碍(ASD)儿童的足尖行走行为(TWB)分类仍是一个存在争议的领域,一些人认为它是更广泛的ITW谱系的一部分,而另一些人则将其视为一个独特的实体。与ASD相关的TWB儿童(自闭症足尖行走-ATW)带来了独特的临床挑战。这一亚组足尖行走的患病率更高,其步态模式往往与潜在的神经发育差异有关,常常导致对传统治疗方法的抵抗增加以及持续和复发率升高。本叙述性综述旨在总结关于ATW干预措施的现有证据,突出与ITW的差异,并讨论对临床实践的影响。

方法

进行了文献检索,包括涉及ASD儿童足尖行走干预措施的文章。

结果

文献有限且异质性较大。已确定的干预措施包括物理治疗、矫形器、肉毒杆菌毒素注射、连续石膏固定和外科手术。有效性证据稀缺,大多数研究由小病例系列组成。ATW在病理生理学和临床表现的某些方面与经典ITW不同。治疗决策应在潜在益处和风险之间取得平衡,特别是在石膏固定期间反复接触麻醉与早期手术选择方面。

结论

管理ATW的证据有限。虽然与ITW进行比较可能有用,但临床医生必须认识到它们具有不同的特征。未来的研究应侧重于标准化定义和对照试验,以指导管理。

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